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Merck
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Key Documents

Altri documenti

MAB344

Sigma-Aldrich

Anti-O1 Antibody, clone 59

clone 59, Chemicon®, from mouse

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

100

Forma dell’anticorpo

saturated ammonium sulfate (SAS) precipitated

Clone

59, monoclonal

Reattività contro le specie

chicken, rat, mouse, human

Produttore/marchio commerciale

Chemicon®

tecniche

immunohistochemistry: suitable

Isotipo

IgM

Condizioni di spedizione

wet ice

modifica post-traduzionali bersaglio

unmodified

Specificità

Recognizes Oligodendrocyte marker O1. Also reacts with certain galactolipids in sperm (see Additional Information library for list).

Immunogeno

White matter of corpus callosum from rat brain.

Applicazioni

Anti-O1 Antibody, clone 59 is an antibody against O1 for use in IH.
Immunohistochemistry: 10-20 μg/mL on unfixed, shock frozen tissue.

Note: 01 is a lipid which is released from the membrane by alcohol.

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Stato fisico

Format: Purified
Liquid. Buffer = 0.05 M Potassium Phosphate, 0.3 M NaCl, pH 8.0 with 0.05% sodium azide.

Stoccaggio e stabilità

Maintain lyophilized material at +2–8°C for up to 12 months. After reconstitution maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Risultati analitici

Control
Oligodendrocyte culture, Brain

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Jong-Wan Kim et al.
Folia neuropathologica, 57(1), 24-35 (2019-05-01)
This study was performed to determine whether the disturbed maturation of oligodendrocyte (OL) progenitors might be related to lipopolysaccharide (LPS)-induced hypomyelination. We created organotypic cultures of forebrain slices from neonatal rats and explored the morphological changes of glial cells expressing
Olfactory ensheathing cells exhibit unique migratory, phagocytic, and myelinating properties in the X-irradiated spinal cord not shared by Schwann cells.
Karen L Lankford,Masanori Sasaki,Christine Radtke,Jeffery D Kocsis
Glia null
Developmental expression in central and peripheral nervous system of oligodendrocyte cell surface antigens (O antigens) recognized by monoclonal antibodies.
M Schachner et al.
Developmental biology, 83(2), 328-338 (1981-04-30)
Administration of dexamethasone to neonatal rats induces hypomyelination and changes in the morphology of oligodendrocyte precursors.
Kim, JW; Kim, YJ; Chang, YP
Comparative Medicine null
Zhong Liu et al.
Stem cells and development, 26(3), 177-188 (2016-10-21)
Neural stem cells (NSCs) have the capacity to differentiate into neurons, astrocytes, and oligodendrocytes, and therefore represent a promising donor tissue source for treating neurodegenerative diseases and repairing injuries of the nervous system. However, it remains unclear how canonical microRNAs
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Articoli

Robust Differentiation of Human iPSCs into Lineage-Specific Neurons and Glial Cells Utilizing Dual-SMAD Inhibition

Human iPSC neural differentiation media and protocols used to generate neural stem cells, neurons and glial cell types.

Protocolli

Neural Stem Cell Culture Protocols

Step-by-step culture protocols for neural stem cell culture including NSC isolation, expansion, differentiation and characterization.

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.