MAB2168
Anti-Huntingtin Protein Antibody, a.a. 2146-2541, clone HU-2E8
ascites fluid, clone HU-2E8, Chemicon®
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About This Item
Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Prodotti consigliati
Origine biologica
mouse
Livello qualitativo
Forma dell’anticorpo
ascites fluid
Tipo di anticorpo
primary antibodies
Clone
HU-2E8, monoclonal
Reattività contro le specie
monkey, human
Produttore/marchio commerciale
Chemicon®
tecniche
ELISA: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable
Isotipo
IgG1
N° accesso NCBI
N° accesso UniProt
Condizioni di spedizione
dry ice
modifica post-traduzionali bersaglio
unmodified
Informazioni sul gene
human ... HTT(3064) , SLC6A4(6532)
Specificità
Reacts with Huntingtin protein from human and monkey. Weak to no reactivity with mouse. Has not been tested on other species.
Immunogeno
Epitope: a.a. 2146-2541
Human huntingtin fragment from aa 2146 to 2541 as a fusion protein.
Applicazioni
Anti-Huntingtin Protein Antibody, a.a. 2146-2541, clone HU-2E8 is an antibody against Huntingtin Protein for use in ELISA, WB, IC, IH(P).
ELISA: 1:500-1:5,000
Western blot: 1:500-1:5,000
Immunohistochemistry on frozen and microwave oven treated paraffin sections
(human tissue): 1:500-1:5,000
Immunocytochemistry on transfected cells: 1:500-1:5,000
Optimal working dilutions must be determined by the end user.
Western blot: 1:500-1:5,000
Immunohistochemistry on frozen and microwave oven treated paraffin sections
(human tissue): 1:500-1:5,000
Immunocytochemistry on transfected cells: 1:500-1:5,000
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Neurodegenerative Diseases
Stato fisico
Ascites fluid. Liquid, does not contain any preservative.
Note legali
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Raccomandato
N° Catalogo
Descrizione
Determinazione del prezzo
Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
nwg
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Increased apoptosis, Huntingtin inclusions and altered differentiation in muscle cell cultures from Huntington's disease subjects.
Ciammola, A; Sassone, J; Alberti, L; Meola, G; Mancinelli, E; Russo, MA; Squitieri, F; Silani, V
Cell Death and Differentiation null
Huntingtin distribution among striatal output neurons of normal rat brain
Fusco, F.R. et al.
Neuroscience Letters, 339, 53-56 (2003)
Impaired Ganglioside Metabolism in Huntington's Disease and Neuroprotective Role of GM1.
Maglione V, Marchi P, Di Pardo A, Lingrell S, Horkey M, Tidmarsh E, Sipione S
The Journal of Neuroscience null
Paula A Desplats et al.
Neurobiology of disease, 31(3), 298-308 (2008-07-04)
Transcriptional dysregulation has emerged as a central pathogenic mechanism in Huntington's disease (HD), which is associated with neuropathological changes predominantly in the striatum. Here we demonstrate that expression of Bcl11b (a.k.a. CTIP2), a transcription factor exhibiting highly-enriched localization in adult
F R Fusco et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 19(4), 1189-1202 (1999-02-10)
Immunohistochemistry and single-cell RT-PCR were used to characterize the localization of huntingtin and/or its mRNA in the major types of striatal neurons and in corticostriatal projection neurons in rats. Single-label immunohistochemical studies revealed that striatum contains scattered large neurons rich
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