MAB2053

Anti-Disialoganglioside GD3 Antibody, clone MB3.6

clone MB3.6, Chemicon^®, from mouse

• Sinonimo/i: GD3 Antibody
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 100
• Forma dell’anticorpo: purified antibody
• Tipo di anticorpo: primary antibodies
• Clone: MB3.6, monoclonal
• Reattività contro le specie: human
• Produttore/marchio commerciale: Chemicon^®
• tecniche: flow cytometry: suitable; immunofluorescence: suitable; immunohistochemistry: suitable
• Isotipo: IgG3
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified

Descrizione

Specificità

Reacts specifically with human GD3 ganglioside (Cheresh et al., 1984). No cross-reactivity with other gangliosides purified from neuroblastoma or melanoma cells.

Immunogeno

FM9 melanoma cells

Applicazioni

Anti-Disialoganglioside GD3 Antibody, clone MB3.6 is an antibody against Disialoganglioside GD3 for use in FC, IF, IH.

Immunohistochemistry (frozen tissue sections)

Immunofluorescence of cells in culture

Flow cytometry: 1-2 μg per 10E6 cells

Lysis of GD3 positive (melanoma) cells in presence of complement (Cheresh et al., 1985).

Induction of antibody dependent cellular cyotoxicity (ADCC) {Ortaldo JR et al 1987 J Immunol 138(10):3566-3572.

TLC analysis: Sjoberg, ER (1995) J. Biol. Chem. 270(7):2921-2930.{http://www.jbc.org/cgi/content/full/270/7/2921}





Optimal working dilutions must be determined by end user.

Stato fisico

Format: Purified

Liquid in 0.02M PB pH 7.6, 0.25M NaCl containing 0.1% NaN3.

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable