Passa al contenuto
Merck
Tutte le immagini(3)

Key Documents

View All Documentation

HIGFMAG-52K

Millipore

MILLIPLEX® Human IGF-I, II Magnetic Bead Panel - Endocrine Assay

The Human IGF Panel, using the Luminex xMAP technology, enables the simultaneous analysis of one or both IGF-I and IGF-II protein biomarkers in human serum, plasma and cell/tissue culture samples.

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(3)

About This Item

Codice UNSPSC:
12161503
eCl@ss:
32161000
NACRES:
NA.84

Livello qualitativo

200

Reattività contro le specie

human

Produttore/marchio commerciale

Milliplex®

assay range

accuracy: 89%
(IGF-II)
sensitivity: 19 pg/mL
(MinDC+2SD; IGF-I)
sensitivity: 919 pg/mL
(MinDC+2SD; IGF-II)
standard curve range: 41-30,000 pg/mL
(IGF-I)
standard curve range: 892-650,000 pg/mL
(IGF-II)
inter-assay cv: <15%
intra-assay cv: <10%
(IGF-I)
inter-assay cv: <15%
intra-assay cv: <10%
(IGF-II)

tecniche

multiplexing: suitable

N° accesso UniProt

P05019

Metodo di rivelazione

fluorometric (Luminex xMAP)

Condizioni di spedizione

wet ice

Informazioni sul gene

human ... IGF1(3479)

Categorie correlate

Descrizione generale

Insulin-like Growth Factors I and II are polypeptide, endocrine hormones similar in molecular structure to insulin. Both IGF-I and IGF-II are produced primarily by the liver and their bio-availabilities are regulated by the IGF binding proteins (IGFBPs).

MILLIPLEX® Human IGF-I, II Panel is a 2-plex kit to be used for the quantitative determination of IGF-I and/or IGF-II in human serum, plasma, tissue/cell extracts, or culture media samples. Reagents are included for the extraction of serum and plasma samples resulting in a 1:60 final dilution. This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.

The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Endocrine

Specificità

Cross Reactivty
There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel.
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

Applicazioni

  • Analytes: IGF-I, IGF-II
  • Recommended Sample Type: Human serum, plasma, cell/tissue culture supernatants or lysates
  • Recommended Sample Dilution: Use 25 μL per well of the final 1:60 extracted serum or plasma; Cell/tissue culture supernatants or lysates may require a dilution in appropriate control medium.
  • NOTE: Sample extraction, using the reagents included in the kit, is required for serum and plasma samples. The final dilution for extracted serum or plasma samples is 1:60.
  • Assay Run Time: Overnight (16-20 hours) at 2-8°C
  • Research Category: Metabolism
  • Research Subcategory: Metabolic Disorders

Caratteristiche e vantaggi

Design your multiplex kit by choosing available analytes within this panel.

Confezionamento

96 well plate
Everything you need in a single kit.

Stoccaggio e stabilità

Recommended storage for kit components is 2 - 8°C.

Altre note

Please contact Technical Service for linearity of dilution.
Standard curve range: Refer to analysis sheet for exact standard concentracions.

Note legali

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Avvertenze

Danger

Classi di pericolo

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Flam. Liq. 2 - Met. Corr. 1 - Skin Sens. 1

Codice della classe di stoccaggio

3 - Flammable liquids

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

Effects of maternal obstructive sleep apnoea on fetal growth: a prospective cohort study.
Fung, AM; Wilson, DL; Lappas, M; Howard, M; Barnes, M; O'Donoghue, F; Tong, S; Esdale et al.
Testing null
Kenneth Maleta et al.
The American journal of clinical nutrition, 113(2), 380-390 (2021-01-01)
Insulin-like growth factor I (IGF-I) is the most important hormonal promoter of linear growth in infants and young children. The objectives of this study were to compare plasma IGF-I concentration in a low- compared with a high-income country and characterize
Francesca D'Addio et al.
Nature communications, 13(1), 684-684 (2022-02-05)
Loss of pancreatic beta cells is a central feature of type 1 (T1D) and type 2 (T2D) diabetes, but a therapeutic strategy to preserve beta cell mass remains to be established. Here we show that the death receptor TMEM219 is

Contenuto correlato

Multiplexing Metabolic Syndrome Biomarkers | MILLIPLEX® Assays

Multiplex immunoassays, such as MILLIPLEX® multiplex metabolic assays, are critical in metabolic syndrome research because they provide a full picture of the different conditions related to it, like diabetes and obesity, as well as save time and sample volume.

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.