GF312

SCF Protein, Human Recombinant Animal Free

The Stem cell factor also known as ckit ligand, mast cell growth factor & steel factor (SLF), is a widely expressed 28-40kDa type I transmembrane glycoprotein. Recombinant animal free human SCF is manufactured using all non-animal reagents.

• Sinonimo/i: Stem Cell Factor, ckit Ligand, Mast Cell Growth Factor, Stell Factor, MGF
• Codice UNSPSC: 12352202
• eCl@ss: 32160405
• NACRES: NA.77

Proprietà

• Ricombinante: expressed in E. coli
• Livello qualitativo: 100
• Saggio: >98% (SDS-PAGE and HPLC)
• Impurezze: <0.1 μg/mg protein endotoxin (<1EU/μg)
• N° accesso NCBI: NM_000899.3; NM_003994.4
• N° accesso UniProt: P21583
• Condizioni di spedizione: dry ice

Descrizione

Descrizione generale

Product Source: E. coli

Stem cell factor (SCF), also known as ckit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28-40kDa type I transmembrane glycoprotein. It promotes the survival, differentiation, and mobilization of multiple cell types including myeloid, erythroid, megakaryocytic, lymphoid, germ cell, and melanocyte progenitors. Human SCF manifests low activity on murine cells, while murine and rat SCF are fully active on human cells. Recombinant human SCF is an 18.4 kDa polypeptide containing 165 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF.

Specificità

Cross Reactivty
Monkey

Applicazioni

Research Category
Stem Cell Research

Research Sub Category
Growth Factors & Receptors

Qualità

Bioactivity assay: The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.

Stato fisico

Product is filtered through a 0.2 micron filter before lyophilization.

Recombinant animal free human SCF is manufactured using all non-animal reagents

Stoccaggio e stabilità

Store at -20°C for up to 6 months from date of receipt.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1