ABN1386

Anti-HES-1 Antibody

from rabbit, purified by affinity chromatography

• Sinonimo/i: Class B basic helix-loop-helix protein 39, bHLHb39, Hairy and enhancer of split 1, Hairy homolog, Hairy-like protein, hHL
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Purificato mediante: affinity chromatography
• Reattività contro le specie: mouse
• Reattività contro le specie (prevista in base all’omologia): human (based on 100% sequence homology), monkey (based on 100% sequence homology), hamster (based on 100% sequence homology), horse (based on 100% sequence homology), rat (based on 100% sequence homology)
• tecniche: immunohistochemistry: suitable; western blot: suitable
• N° accesso NCBI: NP_032261
• N° accesso UniProt: P35428
• Condizioni di spedizione: dry ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... HES1(3280) ; mouse ... Hes1(15205)

Descrizione

Descrizione generale

Transcription factor HES-1 (HES-1) also known as Hairy and enhancer of split 1, Hairy homolog, Hairy-like protein, belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box.

Immunogeno

KLH-conjugated linear peptide corresponding to the near N-terminal of Mouse HES-1.

Applicazioni

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected HES-1 in mouse hindbrain, cerebellum and kidney tissue.

This Anti-HES-1 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of HES-1.

Qualità

Evaluated by Western Blotting in mouse brain tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Hes-1 in 10 µg of mouse liver tissue lysate.

Descrizione del bersaglio

~30 kDa observed. Uncharacterized bands maybe observed in some lysates.

Linkage

Replaces: AB15470

Altre note

Concentration: Please refer to lot specific datasheet.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable