ABF219

Anti-SARM Antibody

from rabbit, purified by affinity chromatography

• Sinonimo/i: Sterile alpha and TIR motif-containing protein 1, Sterile alpha and Armadillo repeat protein, Sterile alpha motif domain-containing protein 2, SAM domain-containing protein 2, Tir-1 homolog
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Purificato mediante: affinity chromatography
• Reattività contro le specie: human
• tecniche: immunocytochemistry: suitable; immunofluorescence: suitable; western blot: suitable
• N° accesso UniProt: Q6SZW1
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... SARM1(23098)

Descrizione

Descrizione generale

Sterile alpha and Armadillo repeat protein (SARM), also known as Sterile alpha and TIR motif-containing protein 1 (SARM1) and Sterile alpha motif domain-containing protein 2 (SAMD2), is involved in the innate immnune response. SARM blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88-dependent pathway or non-TLR signaling. SARM is expressed kidney and liver with lower levels found in placenta.

Specificità

This antibody recognizes the C-terminus of SARM.

Immunogeno

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of human SARM.

Applicazioni

Detect Sterile alpha & Armadillo repeat protein using this rabbit polyclonal antibody, Anti-SARM Antibody validated for use in western blotting, ICC & Immunofluorescence.

Immunocytochemistry Analysis: 2 µg/mL from a representative lot detected SARM in Daudi cells.

Immunofluorescence Analysis: 2 µg/mL from a representative lot detected SARM in Daudi cells.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

Qualità

Evaluated by Western Blotting in Daudi cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected SARM in 15 µg of Daudi cell lysate.

Descrizione del bersaglio

~89 kDa observed. Uncharacterized bands may appear in some lysates.

Stato fisico

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Stoccaggio e stabilità

Stable for 1 year at 2-8°C from date of receipt.

Risultati analitici

Control
Daudi cell lysate

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable