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Key Documents

AB9040

Sigma-Aldrich

Anti-Nerve Growth Factor Antibody, pro

serum, Chemicon®

Sinonimo/i:

proNGF

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

Forma dell’anticorpo

serum

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Reattività contro le specie

rat, human, mouse

Produttore/marchio commerciale

Chemicon®

tecniche

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

N° accesso UniProt

Condizioni di spedizione

dry ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... NTF3(4908)

Specificità

Reacts with proNGF.

Immunogeno

Recombinant protein from mouse proNGF.

Applicazioni

Anti-Nerve Growth Factor Antibody, pro is an antibody against Nerve Growth Factor for use in IP, WB, IH.
Research Category
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins
Western blot: 1:250-1:500. Reacts with bands of 30 kD and 32 kD.

Immunohistochemistry: 1:250 on frozen sections.

Immunocytochemistry

Immunoprecipitation

Optimal working dilutions must be determined by the end user.

Stato fisico

Rabbit serum. Liquid.

Stoccaggio e stabilità

Maintain at -20°C in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

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Bernadette Rogez et al.
Veterinary pathology, 57(4), 507-519 (2020-05-01)
Accumulating data highlight the role of neurotrophins and their receptors in human breast cancer. This family includes nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF), both synthetized as proneurotrophins (proNGF and proBDNF). (pro)NGF and (pro)BDNF initiate their biological effects
Sam Faulkner et al.
Oncotarget, 7(19), 28488-28497 (2016-04-14)
The precursor for nerve growth factor (proNGF) is expressed in some cancers but its clinicopathological significance is unclear. The present study aimed to define the clinicopathological significance of proNGF in thyroid cancer. ProNGF expression was analysed by immunohistochemistry in two
Sam Faulkner et al.
FASEB bioAdvances, 2(7), 398-408 (2020-07-18)
Nerve growth factor (NGF) and its receptors are increasingly implicated in cancer progression, but their expression in cervical cancer is unclear. The objective of this study was to define the protein expression of NGF, its precursor (proNGF), as well as
Yohann Demont et al.
The Journal of biological chemistry, 287(3), 1923-1931 (2011-12-01)
The precursor of nerve growth factor (proNGF) has been described as a biologically active polypeptide able to induce apoptosis in neuronal cells, via the neurotrophin receptor p75(NTR) and the sortilin receptor. Herein, it is shown that proNGF is produced and
Mariano Catanesi et al.
Cell biology international, 44(8), 1734-1744 (2020-04-29)
Alzheimer's disease represents the most prevalent neurodegeneration worldwide, clinically characterized by cognitive and memory impairment. New therapeutic approaches are extremely important to counteract this disorder. This research is focused on the potential use of choline alfoscerate in preventing neuronal death

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