AB6021

Anti-Stabilin-1 Antibody, CT

from rabbit

• Sinonimo/i: Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1, MS-1 antigen, common lymphatic endothelial and vascular endothelial receptor-1, fasciclin egf-like, laminin-type egf-like, and link domain-containing scavenger re
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: unpurified
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Reattività contro le specie: human
• tecniche: immunofluorescence: suitable; immunohistochemistry: suitable (paraffin); western blot: suitable
• N° accesso UniProt: Q9NY15
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... STAB1(23166)

Descrizione

Descrizione generale

Stabilin-1 and Stabilin-2 constitute a novel family of fasciclin domain-containing hyaluronan receptor homologs that may play a role in cell-cell and cell-extracellular matrix interactions in vascular function and inflammatory processes. Stabilin-1 is a transmembrane protein, expressed in endothelial cells within the sinusoidal regions of liver, spleen, and lymph tissues as well as macrophages. Stabilin-2 is absent from the latter (Politz, 2002).

Specificità

Other notable species homologies include mouse (87%) and rat (83%).

The antibody recognizes the C-terminus of Stabilin-1 within the cytoplasmic region of a cell.

Immunogeno

Epitope: C-terminus

GST-tagged recombinant protein corresponding to the C-terminus of human Stabilin-1.

Applicazioni

Anti-Stabilin-1 Antibody, C-terminus is an antibody against Stabilin-1 for use in WB, IH(P) & IF.

Immunohistochemistry Analysis: 1:500 dilution from a previous lot detected Stabilin-1 in human placental tertiary villi.
Immunofluorescence Analysis: A previous lot of Anti-Stabilin-1, C-terminus was shown to positively stain using immunofluorescence techniques (Kzhyshkowska, 2008).

Research Category
Cell Structure

Research Sub Category
Adhesion (CAMs)

Qualità

Evaluated by Western blot in HUVEC lysate.
Western blot Analysis: 1:1,000 dilution of this antibody detected Stabilin-1 on 10 µg of HUVEC lysate.

Descrizione del bersaglio

~ 275 kDa

Stato fisico

Format: Unpurified

Unpurified

Unpurified rabbit polyclonal in serum with 0.05% sodium azide.

Stoccaggio e stabilità

Stable for 1 year at -20°C from date of receipt if stored in undiluted aliquots.
Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Risultati analitici

Control
HUVEC lysate.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1