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Key Documents

AB15415

Sigma-Aldrich

Anti-GABARAP Antibody

serum, Chemicon®

Sinonimo/i:

Gamma-aminobutyric acid receptor-associated protein, GABA(A) receptor-associated protein

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

Forma dell’anticorpo

serum

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Reattività contro le specie

human, rat

Produttore/marchio commerciale

Chemicon®

tecniche

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

N° accesso NCBI

N° accesso UniProt

Condizioni di spedizione

wet ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... GABARAP(11337)

Descrizione generale

Autophagy is the process by which cells recycle cytoplasm and dispose of excess or defective organelles. This process is suggested to be involved development, differentiation, growth regulation and tissue remodeling in multicellular organisms. An important inhibitory neurotransmitter, GABA, acts on GABA receptors that are ubiquitously expressed in the CNS. GABARAP has been shown to play a important role in modulating the activities of GABA (A) receptors.

Specificità

GABARAP [Gamma-aminobutyric acid receptor-associated protein, GABA(A) receptor-associated protein].

Immunogeno

Synthetic peptide corresponding to a region within the N-terminus of human GABARAP protein.

Applicazioni

Anti-GABARAP Antibody detects level of GABARAP & has been published & validated for use in IC, IH & WB.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Western blot: 1:100-1:1,000
Immunocytochemistry: 1:100-1:1,000
Immunohistochemistry: 1:100-1:1,000
Optimal working dilutions must be determined by end user.

Stato fisico

Lyophilized. Reconstitute with 50 uL of sterile distilled water. Centrifuge to remove any insoluble material. Contains no preservative.
Serum

Stoccaggio e stabilità

Maintain lyophilized material frozen at -20°C to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1, ACS or better grade) can be added for additional stability.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids


Certificati d'analisi (COA)

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GABAA receptor associated proteins: a key factor regulating GABAA receptor function.
Chen, Zi-Wei and Olsen, Richard W
Journal of Neurochemistry, 100, 279-294 (2007)
Increased susceptibility of cytoplasmic over nuclear polyglutamine aggregates to autophagic degradation.
Iwata, Atsushi, et al.
Proceedings of the National Academy of Sciences of the USA, 102, 13135-13140 (2005)

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