AB10418

Anti-Puma BH3 domain Antibody

from rabbit

• Sinonimo/i: BCL2 binding component 3, Bcl-2 binding component 3, p53 up-regulated modulator of apoptosis
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: purified antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Reattività contro le specie: mouse
• tecniche: western blot: suitable
• N° accesso NCBI: NP_055232
• N° accesso UniProt: Q9BXH1
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: mouse ... Bbc3(170770)

Descrizione

Descrizione generale

PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis

Specificità

Other species have not been tested.

The antibody reacts with the 21 kDa Puma BH3 domain protein.

Immunogeno

This antibody was developed against a synthetic peptide selected from the C-terminal region of human Puma.

Applicazioni

Anti-Puma BH3 domain Antibody is an antibody against Puma BH3 domain for use in WB.

Qualità

Western Blot Analysis: 1:250 dilution of this antibody detected Puma BH3 domain on mouse brain lysate.

Descrizione del bersaglio

21 kDa

Stato fisico

Format: Purified

Risultati analitici

Control
Western Blot : Mouse brain lysate

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable