208690

Calmodulin, Bovine Brain

Calmodulin is a ubiquitous Ca²⁺-binding protein that serves as a physiological effector of a wide range of biological processes. Purified from bovine brain.

• Sinonimo/i: Calmodulin, Bovine Brain, CaM, Ca ²⁺/Calmodulin, CaM, Ca²⁺/Calmodulin
• Numero CAS: 73298-54-1
• Numero MDL: MFCD00131869
• Codice UNSPSC: 12352202

Proprietà

• Livello qualitativo: 100
• Saggio: ≥95% (SDS-PAGE)
• Forma fisica: lyophilized
• Attività specifica: ≥12,500 units/mg protein
• Produttore/marchio commerciale: Calbiochem^®
• Condizioni di stoccaggio: OK to freeze
• Solubilità: aqueous buffer: soluble; water: soluble
• Condizioni di spedizione: ambient
• Temperatura di conservazione: −20°C

Descrizione

Descrizione generale

A ubiquitous Ca²⁺-binding protein distributed in eukaryotic cells that serves as a major physiological effector for a wide range of cellular responses. The Ca²⁺-calmodulin complex is involved in the maintenance of intracellular Ca²⁺ homeostasis, as well as in the regulation of the intracellular concentration of other second messengers, such as cyclic AMP and inositol trisphosphate. Calmodulin purified from bovine brain.



Note: This product is not to be used for animal treatment, in vivo research or in any other contact procedure with livestock.

A ubiquitous Ca²⁺-binding protein that serves as a physiological effector of a wide range of biological processes. Calmodulin purified from bovine brain.

Attenzione

Toxicity: Standard Handling (A)

Definizione di unità

One unit is defined as the amount of calmodulin that gives rise to 50% of the maximal enzyme activation of a standard level of activator-deficient 3ʹ,5ʹ-cyclic nucleotide phosphodiesterase.

Stato fisico

Lyophilized from 150 mM NaCl, 50 mM Tris-HCl, 2 mM EDTA, pH 7.6.

Ricostituzione

Following reconstitution, aliquot and freeze (-20°C or -70°C). Stock solutions are stable for up to 2 months at -20°C or for up to 4 months at -70°C.

Altre note

Carl, A., et al. 1990. J. Physiol.429, 205.
Appleman, M.M., et al. 1985. J. Cyclic Nucleotide and Protein Phosph. Res.10, 417.
Cheung, W.T. 1979. Science207, 19.
Sharma, R.K., and Wang, J.H. 1979. Adv. Cyclic Nucleotide Res.10, 187.
Wang, J.H., and Waisman, D.M. 1979. Curr. Topics Cell. Reg.15, 47.
Watterson, A., et al. 1976. J. Biol. Chem.251, 4501.

Note legali

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3