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Key Documents

14-845-M

Sigma-Aldrich

PIP5K1γ Protein, active, 10 µg

Active, N-terminal 6His-tagged, recombinant human PIP5K1γ, full length. For use in Kinase Assays.

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About This Item

Codice UNSPSC:
12352202
eCl@ss:
32160405
NACRES:
NA.41

Origine biologica

human

Livello qualitativo

Ricombinante

expressed in baculovirus infected Sf21 cells

PM

Mw 77 kDa

Produttore/marchio commerciale

Upstate®

tecniche

activity assay: suitable (kinase)

N° accesso NCBI

N° accesso UniProt

Informazioni sul gene

human ... PIP5K1C(23396)

Descrizione generale

N-terminal 6His-tagged, recombinant human PIP5K1γ, full length.
Product Source: Expressed by baculovirus in Sf21 insect cells

Applicazioni

Active, N-terminal 6His-tagged, recombinant human PIP5K1γ, full length. For use in Kinase Assays.
Research Category
Signaling
Research Sub Category
Oncology

Inflammation & Autoimmune Mechanisms

Diabetes

Alzheimer′s Disease

Neurodegenerative Diseases

Azioni biochim/fisiol

Protein Target: PIP5K1γ
Target Sub-Family: PIPK

Confezionamento

Also available in 250μg size as catalog # 14-845M - Call for pricing and availability.

Qualità

Routinely evaluated in the PIProfiler.

Stato fisico

10µg of enzyme in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 0.2mM PMSF, 1mM benzamidine, 0.1% 2-mercaptoethanol. Frozen solution.
Immobilized metal affinity chromatography (IMAC)

Stoccaggio e stabilità

6 months at -70°C

Altre note

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Note legali

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Brittany D Wright et al.
Journal of biomolecular screening, 20(5), 655-662 (2014-12-24)
Phosphatidylinositol 4-phosphate 5-kinases (PIP5Ks) regulate a variety of cellular processes, including signaling through G protein-coupled receptors (GPCRs), endocytosis, exocytosis, and cell migration. These lipid kinases synthesize phosphatidylinositol 4,5-bisphosphate (PIP2) from phosphatidylinositol 4-phosphate [PI(4)P]. Because small-molecule inhibitors of these lipid kinases

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