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Merck
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Key Documents

14-309

Sigma-Aldrich

PCAF Protein, Active, 50 µg

PCAF recombinant GST fusion protein, for use in Histone Acetyltransferase Assays. (HAT).

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About This Item

Codice UNSPSC:
12352202
eCl@ss:
32160405
NACRES:
NA.32

Ricombinante

expressed in E. coli

Livello qualitativo

PM

Mw 79 kDa

Produttore/marchio commerciale

Upstate®

tecniche

activity assay: suitable (histone acetyltransferase (HAT))

N° accesso NCBI

N° accesso UniProt

Condizioni di spedizione

dry ice

Descrizione generale

Product Source: expressed in E. Coli corresponding to amino acids 352-832

Qualità

routinely evaluated by acetylation of core histones in vitro

Altre note

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Note legali

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Chromosomal protein HMGN1 enhances the acetylation of lysine 14 in histone H3.
Jae-Hwan Lim,Katherine L West,Yaffa Rubinstein,Michael Bergel,Yuri V Postnikov,Michael Bustin
The Embo Journal null
Prabhat Kumar Purbey et al.
Molecular and cellular biology, 29(5), 1321-1337 (2008-12-24)
Special AT-rich binding protein 1 (SATB1) acts as a global regulator of gene expression by recruiting various corepressor or coactivator complexes, thereby establishing a unique chromatin structure at its genomic targets in a context-dependent manner. Although SATB1 acts predominantly as
Giosalba Burgio et al.
Journal of enzyme inhibition and medicinal chemistry, 31(sup3), 75-82 (2016-07-09)
Histones and polyamines are important determinants of the chromatin structure. Histones form the core of nucleosome particles and their modification by acetylation of N-terminal tails is involved in chromatin structural changes and transcriptional regulation. Polyamines, including spermidine, are also targets
R L Schiltz et al.
The Journal of biological chemistry, 274(3), 1189-1192 (1999-01-09)
A number of transcriptional coactivators possess intrinsic histone acetylase activity, providing a direct link between hyperacetylated chromatin and transcriptional activation. We have determined the core histone residues acetylated in vitro by recombinant p300 and PCAF within mononucleosomes. p300 specifically acetylates
Zhaohua Lu et al.
Planta medica, 72(2), 151-155 (2006-02-24)
A recombinant single chain variable-fragment (scFv) antibody against paeoniflorin (PF) was produced using the hybridoma cell line C31B9. Variable regions of heavy (V (H)) and light (V (L)) chain antibody genes were directly cloned from cDNA resources of hybridoma C31B9

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