07-677-IS

Anti-acetyl-Histone H3 (Lys56) Antibody, Trial Size

from rabbit, purified by affinity chromatography

• Sinonimo/i: Histone H3.1, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/i, Histone H3/j, Histone H3/k, Histone H3/l, H3K56Ac, Histone H3 (acetyl K56), Histone 3, H3, Histone cluster 3, H3, Histone H3 K56ac, Histone H3
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Purificato mediante: affinity chromatography
• Reattività contro le specie: human
• tecniche: ChIP: suitable; dot blot: suitable; western blot: suitable
• N° accesso NCBI: NP_003520
• N° accesso UniProt: P68431
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: acetylation (Lys56)
• Informazioni sul gene: human ... HIST1H3F(8968)

Descrizione

Descrizione generale

Histone H3 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. Acetylation of histone H3 occurs at several different lysine positions in the histone tail and is performed by a family of enzymes known as Histone Acetyl Transferases (HATs).

Specificità

This antibody recognizes Histone H3 acetylated at Lys56.

Immunogeno

Epitope: Acetylated Lys56

KLH-conjugated linear peptide corresponding to human Histone H3 acetylated at Lys56.

Applicazioni

Anti-acetyl-Histone H3 (Lys56) Antibody, Trial Size/ Pack is a rabbit polyclonal antibody for detection of acetyl-Histone H3 (Lys56) also known as H3K56Ac, Histone H3 (acetyl K56) & has been validated in WB, ChIP.

Dot Blot (Specificity) Analysis: A representative lot detected acetyl-Histone H3 (Lys56) in an Absurance Histone H3 Antibody Specificity Array (Cat. No. 16-667).

Chromatin Immunoprecipitation Analysis: A representative lot immunoprecipitated acetyl-Histone H3 (Lys56) from HeLa cells.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Histones

Qualità

Evaluated by Western Blot in HeLa acid extract, sodium butyrate treated HeLa acid extract, colcemid treated HeLa acid extract, recombinant Histone H3, recombinant Histone H4, and recombinant Histone H2A.

Western Blot Analysis: A 1:405 dilution of this antibody detected acetyl-Histone H3 (Lys56) in sodium butyrate treated HeLa acid extract.

Descrizione del bersaglio

~17 kDa observed

Stato fisico

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stoccaggio e stabilità

Stable for 1 year at 2-8°C from date of receipt.

Risultati analitici

Control
HeLa acid extract, sodium butyrate treated HeLa acid extract, colcemid treated HeLa acid extract, recombinant Histone H3, recombinant Histone H4, and recombinant Histone H2A

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable