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Merck
Tutte le immagini(1)

Documenti fondamentali

07-543

Sigma-Aldrich

Anti-p19 ARF Antibody

Upstate®, from rabbit

Sinonimo/i:

Anti-ARF, Anti-CDK4I, Anti-CDKN2, Anti-CMM2, Anti-INK4, Anti-INK4A, Anti-MLM, Anti-MTS-1, Anti-MTS1, Anti-P14, Anti-P14ARF, Anti-P16, Anti-P16-INK4A, Anti-P16INK4, Anti-P16INK4A, Anti-P19, Anti-P19ARF, Anti-TP16

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Tutte le immagini(1)

About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

100

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Purificato mediante

affinity chromatography

Reattività contro le specie

rat, mouse

Produttore/marchio commerciale

Upstate®

tecniche

immunoprecipitation (IP): suitable
western blot: suitable

Isotipo

IgG

N° accesso UniProt

Q8N726

Condizioni di spedizione

wet ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

mouse ... Cdkn2A(12578)
rat ... Cdkn2A(25163)

Specificità

p19 ARF

Immunogeno

Full length mouse p19 ARF fused to GST.

Applicazioni

Detect p19 ARF with Anti-p19 ARF Antibody (Rabbit Polyclonal Antibody), that has been shown to work in IP & WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair

Qualità

Routinely evaluated by immunoblot with lysates from p53 knockout MEF cells.

Descrizione del bersaglio

19kDa

Stato fisico

ImmunoAffinity Purified

Stoccaggio e stabilità

2 years at -20°C from date of shipment

Risultati analitici

Control
Positive Antigen Control: Catalog #12-301, non-stimulated A431 cell lysate. Add 2.5µL of 2-mercaptoethanol/100µL of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for mingels.

Note legali

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Raccomandato

N° Catalogo
Descrizione
Determinazione del prezzo

Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Shubhankar Suman et al.
Aging, 5(8), 607-622 (2013-08-10)
Despite recent epidemiological evidences linking radiation exposure and a number of human ailments including cancer, mechanistic understanding of how radiation inflicts long-term changes in cerebral cortex, which regulates important neuronal functions, remains obscure. The current study dissects molecular events relevant
p19ARF directly and differentially controls the functions of c-Myc independently of p53.
Ying Qi, Mark A Gregory, Zhaoliang Li, Jeffrey P Brousal, Kimberly West, Stephen R Hann
Nature null
Hui-Yi Kua et al.
Nature cell biology, 14(7), 727-737 (2012-06-26)
Defects in stem cell renewal or progenitor cell expansion underlie ageing-related diseases such as osteoporosis. Yet much remains unclear about the mechanisms regulating progenitor expansion. Here we show that the tyrosine kinase c-Abl plays an important role in osteoprogenitor expansion.
S Kitajima et al.
Oncogene, 30(6), 737-750 (2010-10-05)
The reversion-inducing cysteine-rich protein with Kazal motifs (RECK) gene had been isolated as an antagonist to RAS signaling; however, the mechanism of its action is not clear. In this study, the effect of loss of RECK function was assessed in
Nicolas Jullien et al.
PloS one, 10(3), e0120010-e0120010 (2015-03-31)
To test the role of wtPIT-1 (PITWT) or PIT-1 (R271W) (PIT271) in somatolactotroph cells, we established, using inducible lentiviral vectors, sublines of GH4C1 somatotroph cells that allow the blockade of the expression of endogenous PIT-1 and/or the expression of PITWT

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