07-373
Anti-acetyl-Histone H2B Antibody
Upstate®, from rabbit
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About This Item
Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Prodotti consigliati
Origine biologica
rabbit
Livello qualitativo
Forma dell’anticorpo
purified antibody
Tipo di anticorpo
primary antibodies
Clone
polyclonal
Reattività contro le specie
human
Produttore/marchio commerciale
Upstate®
tecniche
western blot: suitable
Isotipo
IgG
N° accesso NCBI
N° accesso UniProt
Condizioni di spedizione
dry ice
modifica post-traduzionali bersaglio
acetylation (Lys5,Lys12,Lys15,Lys20)
Informazioni sul gene
human ... H2BC1(255626)
Categorie correlate
Specificità
acetylated Histone H2B
Immunogeno
Synthetic peptide in which there is an acetyl-lysine at residues 5, 12, 15 and 20 of human Histone H2B
Applicazioni
Detect acetyl-Histone H2B also known as Histone H2B with Anti-acetyl-Histone H2B Antibody (Rabbit Polyclonal Antibody), that has been demonstrated to work in WB.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Histones
Histones
Qualità
routinely evaluated by immunoblot in sodium butyrate treated, acid extracted proteins from HeLa cells
Descrizione del bersaglio
15 kDa
Stato fisico
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein A chromatography
Stoccaggio e stabilità
2 years at -20°C
Note legali
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Certificati d'analisi (COA)
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Spatial memory consolidation is associated with induction of several lysine-acetyltransferase (histone acetyltransferase) expression levels and H2B/H4 acetylation-dependent transcriptional events in the rat hippocampus.
Bousiges, O; Vasconcelos, AP; Neidl, R; Cosquer, B; Herbeaux, K; Panteleeva, I; Loeffler et al.
Neuropsychopharmacology null
Snehajyoti Chatterjee et al.
EMBO molecular medicine, 10(11) (2018-10-03)
Chromatin acetylation, a critical regulator of synaptic plasticity and memory processes, is thought to be altered in neurodegenerative diseases. Here, we demonstrate that spatial memory and plasticity (LTD, dendritic spine formation) deficits can be restored in a mouse model of
A novel activator of CBP/p300 acetyltransferases promotes neurogenesis and extends memory duration in adult mice.
Chatterjee, S; Mizar, P; Cassel, R; Neidl, R; Selvi, BR; Mohankrishna, DV; Vedamurthy et al.
The Journal of Neuroscience null
Frederick A Schroeder et al.
PloS one, 8(8), e71323-e71323 (2013-08-24)
Psychiatric diseases, including schizophrenia, bipolar disorder and major depression, are projected to lead global disease burden within the next decade. Pharmacotherapy, the primary--albeit often ineffective--treatment method, has remained largely unchanged over the past 50 years, highlighting the need for novel
Benjamin E L Lauffer et al.
The Journal of biological chemistry, 288(37), 26926-26943 (2013-07-31)
Histone deacetylases (HDACs) are critical in the control of gene expression, and dysregulation of their activity has been implicated in a broad range of diseases, including cancer, cardiovascular, and neurological diseases. HDAC inhibitors (HDACi) employing different zinc chelating functionalities such
Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..
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