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Merck
Tutte le immagini(2)

Documenti

06-709

Sigma-Aldrich

Anti-Gq/11α Antibody, CT

Upstate®, from rabbit

Sinonimo/i:

Anti-FBH, Anti-FHH2, Anti-GNA-11, Anti-HG1K, Anti-HHC2, Anti-HYPOC2

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

100

Forma dell’anticorpo

purified immunoglobulin

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Reattività contro le specie

human, mouse

Produttore/marchio commerciale

Upstate®

tecniche

immunoprecipitation (IP): suitable
western blot: suitable

Isotipo

IgG

N° accesso NCBI

NM_002067
NM_002072

N° accesso UniProt

P29992

Condizioni di spedizione

wet ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... GNA11(2767)
mouse ... Gna11(14672)

Specificità

Gqα and G11α

Immunogeno

peptide (QLNLKEYNLV) corresponding to amino acids 350-359 of Gqα or G11α

Applicazioni

Research Category
Signaling
Research Sub Category
GPCR, cAMP/cGMP & Calcium Signaling
This Anti-Gq/11α Antibody, CT is validated for use in IP, WB for the detection of Gq/11α.

Qualità

routinely evaluated by immunoblot on rat brain microsomal preparation

Descrizione del bersaglio

42kDa

Stato fisico

Format: Purified
PBS, pH 7.4
Protein A chromatography

Stoccaggio e stabilità

2 years at -20°C

Note legali

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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4-Hydroxynonenal, an aldehydic product of lipid peroxidation, impairs signal transduction associated with muscarinic acetylcholine and metabotropic glutamate receptors: possible action on G alpha(q/11).
Blanc, E M, et al.
Journal of Neurochemistry, 69, 570-580 (1997)
Justyna Róg et al.
Biochimica et biophysica acta. Molecular basis of disease, 1865(6), 1138-1151 (2019-01-27)
Pathophysiology of Duchenne Muscular Dystrophy (DMD) is still elusive. Although progressive wasting of muscle fibres is a cause of muscle deterioration, there is a growing body of evidence that the triggering effects of DMD mutation are present at the earlier
P Cuq et al.
European journal of pharmacology, 315(2), 213-219 (1996-11-14)
The nature of the pertussis toxin-insensitive G-protein involved in muscarinic-mediated phosphoinositides breakdown and contraction of isolated smooth muscle cells from the circular layer of the rabbit caecum was investigated. Immunoblotting of membrane proteins using affinity purified antibodies directed against different
M Côté et al.
Endocrinology, 138(8), 3299-3307 (1997-08-01)
In 3-day primary cultures of rat glomerulosa cells, a 30-min pre-incubation with either 10 microM colchicine (a microtubule-disrupting agent) or 10 microM cytochalasin B (a microfilament-disrupting agent) decreased angiotensin II (Ang II)-induced inositol phosphate accumulation by 50%. Moreover, both drugs
B Kühn et al.
Molecular endocrinology (Baltimore, Md.), 10(12), 1697-1707 (1996-12-01)
In several cell systems histamine has been shown to stimulate both adenylyl cyclase and phospholipase C through activation of a G protein-coupled H2 receptor. To analyze the bifurcating signal emanating from the activated H2 receptor and to identify the G
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