Passa al contenuto
Merck
Tutte le immagini(1)

Key Documents

05-545

Sigma-Aldrich

Anti-PP2A Antibody, C subunit, clone 7A6

culture supernatant, clone 7A6, Upstate®

Sinonimo/i:

Anti-NEDLBA, Anti-PP2CA, Anti-PP2Calpha, Anti-RP-C

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali


About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

Forma dell’anticorpo

culture supernatant

Tipo di anticorpo

primary antibodies

Clone

7A6, monoclonal

Reattività contro le specie

mouse, Saccharomyces cerevisiae, human

Produttore/marchio commerciale

Upstate®

tecniche

immunoprecipitation (IP): suitable
western blot: suitable

Isotipo

IgG

N° accesso NCBI

N° accesso UniProt

Condizioni di spedizione

dry ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... PPP2CA(5515)

Specificità

Recognizes the catalytic subunit of PP2A.

Immunogeno

peptide (C-bARRTPDYFL) corresponding to amino acids 302-309 of human PP2A catalytic subunit

Applicazioni

Anti-PP2A Antibody, C subunit, clone 7A6 detects level of PP2A & has been published & validated for use in IP & WB.
Research Category
Signaling

Neuroscience
Research Sub Category
Kinases & Phosphatases

Neurodegenerative Diseases

Qualità

routinely evaluated by immunoblot on RIPA lysates from A431 cells

Descrizione del bersaglio

36 kDa

Stato fisico

Cell culture supernatant containing 30% glycerol and 0.05% sodium azide as a preservative.
Unpurified

Stoccaggio e stabilità

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Risultati analitici

Control
Positive Antigen Control: Catalog #12-301, non-stimulated A431 cell lysate. Add 2.5µL of 2-mercaptoethanol/100µL of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for minigels.

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Note legali

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Non trovi il prodotto giusto?  

Prova il nostro Motore di ricerca dei prodotti.

Raccomandato

Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

Modeling initiation of Ewing sarcoma in human neural crest cells.
von Levetzow, C; Jiang, X; Gwye, Y; von Levetzow, G; Hung, L; Cooper, A; Hsu, JH; Lawlor, ER
Testing null
Regulation of L-type calcium channel and delayed rectifier potassium channel activity by p21-activated kinase-1 in guinea pig sinoatrial node pacemaker cells.
Ke, Y; Lei, M; Collins, TP; Rakovic, S; Mattick, PA; Yamasaki, M; Brodie, MS; Terrar, DA; Solaro, RJ
Circulation Research null
Chang Y Guo et al.
The Journal of biological chemistry, 277(7), 4839-4844 (2001-11-28)
Ionizing radiation (IR) is known to activate multiple cell cycle checkpoints that are thought to enhance the ability of cells to respond to DNA damage. Protein phosphatase 2A (PP2A) has been implicated in IR-induced activation of checkpoints; therefore, Jurkat cells
Loss of protein phosphatase 2A expression correlates with phosphorylation of DP-1 and reversal of dysplasia through differentiation in a conditional mouse model of cancer progression.
Maddalena T Tilli, Shawnte L Hudgins, M Silvina Frech, Ewa D Halama, Jean-Pierre Renou et al.
Cancer Research null
Protein phosphatase 2A subunit assembly: the catalytic subunit carboxy terminus is important for binding cellular B subunit but not polyomavirus middle tumor antigen.
Ogris, E, et al.
Oncogene, 15, 911-917 (1997)

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.