05-182
Anti-FAK Antibody, clone 2A7
clone 2A7, Upstate®, from mouse
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About This Item
Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Prodotti consigliati
Origine biologica
mouse
Livello qualitativo
Forma dell’anticorpo
purified immunoglobulin
Tipo di anticorpo
primary antibodies
Clone
2A7, monoclonal
Reattività contro le specie
human, mouse, rat, avian
Produttore/marchio commerciale
Upstate®
tecniche
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
Isotipo
IgG1
N° accesso NCBI
N° accesso UniProt
Condizioni di spedizione
wet ice
modifica post-traduzionali bersaglio
unmodified
Informazioni sul gene
human ... PTK2(5747)
Specificità
Recognizes FAK.
Immunogeno
Mixture of affinity-purified tyrosine phosphoproteins from chick embryo fibroblasts expressing p125FAK.
Applicazioni
Anti-FAK Antibody, clone 2A7 detects level of FAK & has been published & validated for use in IC & IP.
Not recommended in Western Blot
Research Category
Signaling
Signaling
Research Sub Category
Cytoskeletal Signaling
Cytoskeletal Signaling
Qualità
routinely evaluated by immunoprecipitation of FAK from a mouse 3T3/A31 RIPA cell lysate, subsequently immunobloted with Anti-FAK (Catalog #06-543)
Descrizione del bersaglio
125 kDa
Linkage
Replaces: 04-591
Stato fisico
Format: Purified
Protein G Purified
Protein G Purified immunoglobulin in Protein G Purified immunoglobulin in Purified immunoglobulin in 10mM PBS, pH 7.4 containing no preservatives.
Stoccaggio e stabilità
Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Risultati analitici
Control
Expressed in most tissue, 3T3/A31 cell lysate
Expressed in most tissue, 3T3/A31 cell lysate
Note legali
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Raccomandato
N° Catalogo
Descrizione
Determinazione del prezzo
Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 2
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Tyrosine phosphorylation of paxillin and focal adhesion kinase during insulin-like growth factor-I-stimulated lamellipodial advance.
Leventhal, P S, et al.
The Journal of Biological Chemistry, 272, 5214-5218 (1997)
Ambivalent role of pFAK-Y397 in serous ovarian cancer--a study of the OVCAD consortium.
Aust, S; Auer, K; Bachmayr-Heyda, A; Denkert, C; Sehouli, J; Braicu, I; Mahner et al.
Molecular Cancer null
F Burgaya et al.
The Journal of biological chemistry, 272(45), 28720-28725 (1997-11-14)
pp125 focal adhesion kinase (FAK), a cytoplasmic tyrosine kinase transducing signals initiated by integrin engagement and G protein-coupled receptors, is highly expressed in brain. FAK from brain had a higher molecular weight and an increased autophosphorylation activity, than from other
Variations of proline-rich kinase Pyk2 expression correlate with prostate cancer progression.
R Stanzione, A Picascia, P Chieffi, C Imbimbo, A Palmieri, V Mirone, S Staibano, R Franco et al.
Laboratory Investigation; a Journal of Technical Methods and Pathology null
P Derkinderen et al.
Science (New York, N.Y.), 273(5282), 1719-1722 (1996-09-20)
Anandamide is an endogenous ligand for central cannabinoid receptors and is released after neuronal depolarization. Anandamide increased protein tyrosine phosphorylation in rat hippocampal slices and neurons in culture. The action of anandamide resulted from the inhibition of adenylyl cyclase and
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