M-065
(±)-MDEA solution
1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
Sinonimo/i:
(±)-3,4-Methylenedioxyethylamphetamine
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About This Item
Formula empirica (notazione di Hill):
C12H17NO2
Numero CAS:
Peso molecolare:
207.27
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24
Prodotti consigliati
Grado
certified reference material
Forma fisica
liquid
Caratteristiche
Snap-N-Spike®/Snap-N-Shoot®
Confezionamento
ampule of 1 mL
Produttore/marchio commerciale
Cerilliant®
drug control
Narcotic Licence Schedule D (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
Concentrazione
1.0 mg/mL in methanol
tecniche
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
applicazioni
forensics and toxicology
Formato
single component solution
Temperatura di conservazione
2-8°C
Stringa SMILE
CC(CC1=CC=C(OCO2)C2=C1)NCC
InChI
1S/C12H17NO2/c1-3-13-9(2)6-10-4-5-11-12(7-10)15-8-14-11/h4-5,7,9,13H,3,6,8H2,1-2H3
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Descrizione generale
MDEA is an illicit recreational drug of the amphetamine and phenethylamine classes. This analytical reference standard is suitable to use in LC/MS or GC/MS applications for clinical toxicology, forensic analysis, or urine drug testing. A 3,4-methylenedioxy derivative of N-ethylamphetamine, MDEA is abused for its psychedelic effects, similar to those of its structural analog MDMA (Ecstasy).
Applicazioni
- (±)-MDEA Solution for Neurotransmitter Research: Utilized extensively in the study of serotonin release mechanisms, (±)-MDEA-D3 provides a robust tool for examining the biochemical pathways involved in neurotransmitter dynamics, essential for advancements in neuropharmacology (Wen et al., 2024).
- Racemic MDEA Reagent for Pharmacological Studies: This solution is crucial for the synthesis and pharmacological evaluation of new psychoactive substances, enabling researchers to delineate the metabolic and pharmacodynamic profiles of novel therapeutic agents (Boucenna et al., 2023).
- High-Purity (±)-MDEA-D3 Reference Material: As a reference standard, this high-purity material is vital for calibrating analytical instruments like LC-MS/MS, ensuring accuracy and reproducibility in quantitative drug analysis and forensic toxicology (Ghorbani et al., 2020).
- (±)-MDEA-D3 Internal Standard for LC-MS/MS: This deuterated version of MDEA serves as an internal standard in chromatographic analyses, enhancing the precision of quantitative measurements in complex biological matrices (Tian et al., 2021).
- (±)-MDEA-D3 Solution for Pharmaceutical Cannabinoid Profiling: Employed in cannabinoid biosynthesis research, (±)-MDEA-D3 aids in the profiling and characterization of cannabinoids, supporting the development of cannabis-based pharmaceuticals with targeted therapeutic effects (Irani et al., 2018).
Note legali
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Avvertenze
Danger
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
Organi bersaglio
Eyes
Codice della classe di stoccaggio
3 - Flammable liquids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
49.5 °F - closed cup
Punto d’infiammabilità (°C)
9.7 °C - closed cup
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Jin Young Kim et al.
Archives of pharmacal research, 31(12), 1644-1651 (2008-12-23)
A liquid chromatography-electrospray ionization-tandem mass spectrometric (LC-ESI-MS/MS) method was developed and validated for the simultaneous detection and quantification of seven amphetamine derivatives (amphetamine (AP), methamphetamine (MA), 3,4-methylenedioxy-N-amphetamine (MDA), 3,4-methylenedioxy-N-methamphetamine (MDMA), 3,4-methylenedioxy-N-ethylamphetamine (MDEA), N,N-dimethylamphetamine (DMA), and N,N-dimethylamphetamine-N-oxide (DMANO)) in human urine.
Melanie Mueller et al.
Synapse (New York, N.Y.), 65(10), 983-990 (2011-03-02)
3,4-Methylenedioxymethamphetamine (MDMA)'s O-demethylenated metabolite, 3,4-dihydroxymethamphetamine (HHMA), has been hypothesized to serve as a precursor for the formation of toxic catechol-thioether metabolites (e.g., 5-N-acetylcystein-S-yl-HHMA) that mediate MDMA neurotoxicity. To further test this hypothesis, HHMA formation was blocked with dextromethorphan (DXM), which
Tamer Awad et al.
Journal of chromatographic science, 48(9), 726-732 (2010-09-30)
Three regioisomeric 3,4-methylenedioxyphenethylamines having the same molecular weight and major mass spectral fragments of equal mass have been reported as drugs of abuse in forensic studies in recent years. These compounds are 3,4-methylenedioxy-N-ethylamphetamine (MDEA), 3,4-methylenedioxy-N,N-dimethylamphetamine (MDMMA), and N-methyl-1-(3,4-methylenedioxyphenyl)-2-butanamine (MBDB). A
R W Romberg et al.
Journal of analytical toxicology, 35(1), 15-22 (2011-01-12)
This study evaluated the potential for partial separation of drugs from their deuterated internal standards using Cerex(®) Polycrom™ CLIN II solid-phase extraction (SPE) cartridges. After elution from the column and derivatization, gas chromatography-mass spectrometry results showed that the target compound
Jozef Hritz et al.
Journal of medicinal chemistry, 51(23), 7469-7477 (2008-11-13)
Cytochrome P450s (CYPs) exhibit a large plasticity and flexibility in the active site allowing for the binding of a large variety of substrates. The impact of plasticity and flexibility on ligand binding is investigated by docking 65 known CYP2D6 substrates
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