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Merck
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Key Documents

Altri documenti

H-125

Supelco

5beta/6beta-Hydroxy Lurasidone (Mixture of Diastereomers) solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Formula empirica (notazione di Hill):
C28H36N4O3S
Peso molecolare:
508.68
Codice UNSPSC:
41116107
NACRES:
NA.24

Grado

certified reference material

Livello qualitativo

300

Forma fisica

liquid

Caratteristiche

Snap-N-Spike®/Snap-N-Shoot®

Confezionamento

ampule of 1 mL

Produttore/marchio commerciale

Cerilliant®

Concentrazione

1.0 mg/mL in methanol

tecniche

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

applicazioni

clinical testing

Formato

single component solution

Temperatura di conservazione

−20°C

Descrizione generale

Hydroxylurasidone is the most abundant metabolite of lurasidone in urine. Lurasidone, marketed under the trade name Latuda®, is a new atypical antipsychotic developed for the treatment of schizophrenia and episodes of depression in adults with bipolar disorder (manic depression). A certified solution standard suitable for use in LC/MS or GC/MS applications for clinical toxicology, forensic analysis, pharmaceutical research, or urine drug testing.

Note legali

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Latuda is a registered trademark of Dainippon Sumitomo Pharma Co., Ltd.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Avvertenze

Danger

Indicazioni di pericolo

H225,H301 + H311 + H331,H370

Classi di pericolo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organi bersaglio

Eyes

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

49.5 °F - closed cup

Punto d’infiammabilità (°C)

9.7 °C - closed cup

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Eleonora Lapi et al.
Molecular cell, 32(6), 803-814 (2008-12-30)
p73 has been identified as a structural and functional homolog of the tumor suppressor p53. The transcriptional coactivator Yes-associated protein (YAP) has been demonstrated to interact with and to enhance p73-dependent apoptosis in response to DNA damage. Here, we show
Christina J Matheny et al.
Chemistry & biology, 20(11), 1352-1363 (2013-11-05)
Phenotypic high-throughput chemical screens allow for discovery of small molecules that modulate complex phenotypes and provide lead compounds for novel therapies; however, identification of the mechanistically relevant targets remains a major experimental challenge. We report the application of sequential unbiased
Peng Wang et al.
Nature medicine, 21(4), 383-388 (2015-03-10)
Types 1 and 2 diabetes affect some 380 million people worldwide. Both ultimately result from a deficiency of functional pancreatic insulin-producing beta cells. Beta cells proliferate in humans during a brief temporal window beginning around the time of birth, with
Justin H Hwang et al.
Journal of virology, 88(20), 12055-12064 (2014-08-15)
Murine polyomavirus small t antigen (PyST) regulates cell cycle, cell survival, apoptosis, and differentiation and cooperates with middle T antigen (MT) to transform primary cells in vitro and in vivo. Like all polyomavirus T antigens, PyST functions largely via its

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