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855776C

Avanti

19:0 Lyso PC

Avanti Research™ - A Croda Brand 855776C

Sinonimo/i:

1-nonadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine

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About This Item

Formula empirica (notazione di Hill):
C27H56NO7P
Numero CAS:
108273-88-7
Peso molecolare:
537.71
Codice UNSPSC:
51191904
NACRES:
NA.25

Saggio

>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)

Forma fisica

liquid

Confezionamento

pkg of 1 × 2.5 mL (855776C-25mg)

Produttore/marchio commerciale

Avanti Research™ - A Croda Brand 855776C

Concentrazione

10 mg/mL (855776C-25mg)

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Categorie correlate

Descrizione generale

Lysophosphatidylcholine (LPC) is a bioactive proinflammatory lipid secreted on pathological response. It has a choline group at its polar head.

Applicazioni

19:0 Lyso PC has been used for the quantification of lysophosphatidylcholine (LPC) in microsomes by mass spectrometry. It has also been used for plasma lipidome analysis of cows.

Azioni biochim/fisiol

Lysophosphatidylcholine (LPC) modifies various biological functions in different cell-types, like endothelial cells, smooth muscle cells, monocytes, macrophages and T-cells. It is associated with atherosclerosis and inflammatory diseases. LPC stimulates many second messengers including, protein kinase C, extracellular-signal-regulated kinases and protein tyrosine kinases.

Confezionamento

5 mL Clear Glass Sealed Ampule (855776C-25mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pittogrammi

Skull and crossbonesHealth hazard
GHS06,GHS08

Avvertenze

Danger

Classi di pericolo

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Organi bersaglio

Central nervous system, Liver,Kidney

Classe di pericolosità dell'acqua (WGK)

WGK 3

Certificati d'analisi (COA)

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Architecture of lipid droplets in endoplasmic reticulum is determined by phospholipid intrinsic curvature
Choudhary V, et al.
Current Biology, 28(6), 915-926 (2018)
Altered plasma lipidome profile of dairy cows with fatty liver disease
Gerspach C, et al.
Research in Veterinary Science, 110, 47-59 (2017)
Ruichuan Yin et al.
Nature protocols, 14(12), 3445-3470 (2019-11-15)
Mass spectrometry imaging (MSI) enables label-free spatial mapping of hundreds of biomolecules in tissue sections. This capability provides valuable information on tissue heterogeneity that is difficult to obtain using population-averaged assays. Despite substantial developments in both instrumentation and methodology, MSI
Sidra Iqbal et al.
Plant physiology and biochemistry : PPB, 147, 101-112 (2019-12-20)
Plant phospholipase A (PLA) and C (PLC) families are least explored in terms of structure, diversity and their roles in membrane lipid remodeling under stress conditions. In this study, we performed gene family analysis, determined gene expression in different tissues
Analysis of phospholipid species in rat peritoneal surface layer by liquid chromatography/electrospray ionization ion-trap mass spectrometry
Gao F, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1761(7), 667-676 (2006)
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