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791268P

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DTPA-BSA (Gd)

DTPA-bis(stearylamide) (gadolinium salt), powder

Sinonimo/i:

(diethylenetriaminepentaacetic acid)-bis(stearylamide) (gadolinium salt); Gd-DTPA-BSA

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About This Item

Formula empirica (notazione di Hill):
C50H94GdN5O8
Numero CAS:
186796-30-5
Peso molecolare:
1050.56
Codice UNSPSC:
12352211
NACRES:
NA.25

Saggio

>99% (TLC)

Forma fisica

powder

Confezionamento

pkg of 1 × 100 mg (791268P-100mg)

Produttore/marchio commerciale

Avanti Polar Lipids 791268P

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Categorie correlate

Descrizione generale

DTPA-BSA (Gd) (diethylenetriaminepentaacetic acid)-bis(stearylamide) (gadolinium salt)) is an amphiphilic molecule with paramagnetic property.

Applicazioni

DTPA-BSA (Gd) (diethylenetriaminepentaacetic acid)-bis(stearylamide) (gadolinium salt)) has been used:
  • in the preparation of nontargeting (NT) gadolinium peptide amphiphile micelles (PAMs) for the magnetic resonance imaging (MRI) of atherosclerotic lesions
  • as a MRI agent in the preparation of lipid-like nanoparticles (LLNs) for small interfering RNA (siRNA) encapsulation
  • as a MRI agent in the preparation of paramagnetic saposin C and dioleylphosphatidylserine (SapC-DOPS) vesicles for imaging glioblastoma multiforme (GBM) tumors

Azioni biochim/fisiol

Gd-DTPA-BSA is useful as magnetic resonance imaging (MRI) agent and the gadolinium ion enables the generation of bright images by lowering the longitudinal relaxation time.

Confezionamento

5 mL Amber Glass Screw Cap Vial (791268P-100mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Codice della classe di stoccaggio

11 - Combustible Solids

Certificati d'analisi (COA)

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Geralda A F van Tilborg et al.
Bioconjugate chemistry, 17(3), 741-749 (2006-05-18)
Apoptosis, or programmed cell death, plays an important role in the etiology of a variety of diseases, including cancer and myocardial infarction. Visualization of apoptosis would allow both early detection of therapy efficiency and evaluation of disease progression. To that
Sang Pil Yoo et al.
ACS omega, 1(5), 996-1003 (2016-12-06)
The leading causes of morbidity and mortality globally are cardiovascular diseases, and nanomedicine can provide many improvements including disease-specific targeting, early detection, and local delivery of diagnostic agents. To this end, we designed fibrin-binding, peptide amphiphile micelles (PAMs), achieved by
F Jasanada et al.
Bioconjugate chemistry, 7(1), 72-81 (1996-01-01)
In order to use the LDL receptor pathway to target radionuclides to cancer sites for imaging and diagnostic purposes, a labeling procedure of LDL with 111In using the DTPA-bis(stearylamide) (L) has been developed. This bifunctional ligand is intended to be
Dual-functional lipid-like nanoparticles for delivery of mRNA and MRI contrast agents
Luo X, et al.
Nanoscale, 9(4), 1575-1579 (2017)

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