780200P
Avanti
16:0 PE MCC
1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide] (sodium salt), powder
Sinonimo/i:
1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide] (sodium salt)
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About This Item
Formula empirica (notazione di Hill):
C49H86N2O11PNa
Numero CAS:
Peso molecolare:
933.18
Codice UNSPSC:
12352211
NACRES:
NA.25
Prodotti consigliati
![18:1 PE MCC 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide] (sodium salt), powder](/deepweb/assets/sigmaaldrich/product/images/396/705/1ea79c7e-9376-4ab2-af52-223e46ac9238/640/1ea79c7e-9376-4ab2-af52-223e46ac9238.jpg)
Saggio
>99% (TLC)
Forma fisica
powder
Confezionamento
pkg of 1 × 25 mg (780200P-25mg)
Produttore/marchio commerciale
Avanti Research™ - A Croda Brand 780200P
Condizioni di spedizione
dry ice
Temperatura di conservazione
−20°C
Descrizione generale
1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide] (16:0 PE MCC) is a lipid consisting of phosphoethanolamine linked to two palmitic acid through its phosphate group and to a maleimide group by its amino group. It is a maleimide-functionalized lipid.
Applicazioni
16:0 PE MCC (1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide]) may been used in functionalized liposome preparation for drug delivery. It may also be used in liposome preparation for testing drug delivery functionality and as a component in microbubble dispersions.
Azioni biochim/fisiol
1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide](DPPE-MCC) via the maleimide group enables covalent attachment in functionalized liposomes and is useful in peptide transport studies.
Confezionamento
5 mL Amber Glass Screw Cap Vial (780200P-25mg)
Note legali
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Codice della classe di stoccaggio
11 - Combustible Solids
Certificati d'analisi (COA)
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K Gradauer et al.
Journal of controlled release : official journal of the Controlled Release Society, 172(3), 872-878 (2013-10-22)
The aim of the present study was the in vivo evaluation of thiomer-coated liposomes for an oral application of peptides. For this purpose, salmon calcitonin was chosen as a model drug and encapsulated within liposomes. Subsequently, the drug loaded liposomes
K Gradauer et al.
Journal of controlled release : official journal of the Controlled Release Society, 165(3), 207-215 (2012-12-12)
An ideal oral drug carrier should facilitate drug delivery to the gastrointestinal tract and its absorption into the systemic circulation. To meet these requirements, we developed a thiomer-coated liposomal delivery system composed of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and a maleimide-functionalized lipid, to
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