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Documenti fondamentali

W266418

Sigma-Aldrich

(S)-(−)-Perillyl alcohol

≥95%, FG

Sinonimo/i:

p-Mentha-1,8-diene-7-ol

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About This Item

Formula empirica (notazione di Hill):
C10H16O
Numero CAS:
Peso molecolare:
152.23
Numero FEMA:
2664
N° CoE:
2024
Numero MDL:
Codice UNSPSC:
12164502
ID PubChem:
Numero Flavis:
2.060
NACRES:
NA.21
Organolettico:
fatty; green
Grado:
FG
Halal
Kosher
Origine biologica:
synthetic
Allergene alimentare:
no known allergens

Origine biologica

synthetic

Livello qualitativo

Grado

FG
Halal
Kosher

Conformità normativa

EU Regulation 1334/2008 & 178/2002
FDA 21 CFR 117
FDA 21 CFR 172.515

Saggio

≥95%

Attività ottica

[α]20/D −88°, c = 1 in methanol

Indice di rifrazione

n20/D 1.501 (lit.)

P. ebollizione

119-121 °C/11 mmHg (lit.)

Densità

0.96 g/mL at 25 °C (lit.)

applicazioni

flavors and fragrances

Documentazione

see Safety & Documentation for available documents

Allergene alimentare

no known allergens

Organolettico

fatty; green

Stringa SMILE

CC(=C)[C@H]1CCC(CO)=CC1

InChI

1S/C10H16O/c1-8(2)10-5-3-9(7-11)4-6-10/h3,10-11H,1,4-7H2,2H3/t10-/m1/s1
NDTYTMIUWGWIMO-SNVBAGLBSA-N

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Categorie correlate

Applicazioni


  • CYP108N12 initiates p-cymene biodegradation in Rhodococcus globerulus.: This study explores the enzymatic breakdown pathways of monoterpenes, using (S)-(−)-Perillyl alcohol as a precursor, offering insights into microbial degradation processes that could be vital for bioremediation efforts or synthetic biology applications (Giang et al., 2022).

  • Orofacial antinociceptive effects of perillyl alcohol associated with codeine and its possible modes of action.: Research demonstrates the pain-relieving properties of (S)-(−)-Perillyl alcohol when combined with codeine, highlighting its potential for developing new analgesic formulations in dental and facial pain management (Limeira et al., 2022).

  • Orofacial antinociceptive activity of (S)-(-)-perillyl alcohol in mice: a randomized, controlled and triple-blind study.: This study underpins the effectiveness of (S)-(−)-Perillyl alcohol in reducing orofacial pain in a controlled experimental setup, providing a basis for further clinical trials in pain management (Tomaz-Morais et al., 2017).

  • In Vivo Anti-Tumor Activity and Toxicological Evaluations of Perillaldehyde 8,9-Epoxide, a Derivative of Perillyl Alcohol.: Highlights the anti-tumor properties of a novel derivative of (S)-(−)-Perillyl alcohol, suggesting its potential as a therapeutic agent in oncology, with comprehensive studies on its efficacy and safety (Andrade et al., 2016).

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

230.0 °F - closed cup

Punto d’infiammabilità (°C)

110 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Donghak Kim et al.
Biotechnology letters, 31(9), 1427-1431 (2009-05-22)
The catalytic turnover of cytochrome P450( cam ) from Pseudomonas putida requires two auxiliary reduction partners, putidaredoxin (Pd) and putidaredoxin reductase (PdR). We report the functional expression in Escherichia coli of tricistronic constructs consisting of P450( cam ) encoded by
Nonmelanoma skin cancer chemoprevention.
Renata Prado et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 37(11), 1566-1578 (2011-09-08)
Juliana de Saldanha da Gama Fischer et al.
Journal of experimental therapeutics & oncology, 7(4), 285-290 (2009-02-21)
Perillyl alcohol (POH) is a naturally occurring monoterpene with antiangiogenic and anti-tumoral properties. This chemotherapeutic agent has proven effectiveness in several clinical trials, including an ongoing phase I, comprising patients with recurrent glioblastoma multiform (GBM) under treatment with POH by
Tabetha Sundin et al.
Molecular and cellular biochemistry, 375(1-2), 97-104 (2013-01-04)
We previously demonstrated in prostate cancer cells that a phytochemical-perillyl alcohol-and the mechanistic target of rapamycin (mTOR) inhibitor rapamycin rapidly attenuated telomerase activity. Protein levels of the telomerase catalytic subunit reverse transcriptase (hTERT) were diminished in the absence of an
Sjef Cornelissen et al.
Journal of industrial microbiology & biotechnology, 38(9), 1359-1370 (2011-05-12)
Cell physiology is a critical factor determining the efficiency of reactions performed by microbial biocatalysts. In order to develop an efficient biotransformation procedure for the hydroxylation of (S)-limonene to (S)-perillyl alcohol by recombinant Pseudomonas putida cells harboring the cytochrome P450

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