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Documenti fondamentali

W261513

Sigma-Aldrich

Lauric aldehyde

greener alternative

natural, ≥95%, FG

Sinonimo/i:

Dodecyl aldehyde, Aldehyde C12, Dodecanal, Lauraldehyde, Laurinaldehyde

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About This Item

Formula condensata:
CH3(CH2)10CHO
Numero CAS:
Peso molecolare:
184.32
Numero FEMA:
2615
Beilstein:
1703917
Numero CE:
N° CoE:
99c
Numero MDL:
Codice UNSPSC:
12164502
ID PubChem:
Numero Flavis:
5.011
NACRES:
NA.21

Grado

FG
Fragrance grade
Halal
Kosher
natural

Livello qualitativo

agenzia

follows IFRA guidelines
meets purity specifications of JECFA

Conformità normativa

EU Regulation 1223/2009
EU Regulation 1334/2008 & 178/2002
FDA 21 CFR 117
FDA 21 CFR 172.515

Saggio

≥95%

Caratteristiche più verdi

Less Hazardous Chemical Syntheses
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

Indice di rifrazione

n20/D 1.435 (lit.)

P. ebollizione

185 °C/100 mmHg (lit.)

Densità

0.831 g/mL at 25 °C (lit.)

applicazioni

flavors and fragrances

Documentazione

see Safety & Documentation for available documents

Allergene alimentare

no known allergens

Allergene in fragranze

no known allergens

Categoria alternativa più verde

Organolettico

green; floral; citrus; waxy; soapy

Stringa SMILE

CCCCCCCCCCCC=O

InChI

1S/C12H24O/c1-2-3-4-5-6-7-8-9-10-11-12-13/h12H,2-11H2,1H3
HFJRKMMYBMWEAD-UHFFFAOYSA-N

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Descrizione generale

Lauric aldehyde is one of the main aliphatic green volatile compounds in macerated grape cluster stems. It is also one of the key flavor constituents of grapefruit oil.

Applicazioni


  • Utility of ToxTracker in animal alternative testing strategy for fragrance materials.: This study highlights the use of ToxTracker, a suite of reporter cell lines, to evaluate the genetic toxicity of fragrance materials, including lauric aldehyde, offering a potential alternative to animal testing and advancing the safety assessment of consumer products (Thakkar et al., 2023).

  • In vitro evaluation of polymeric micelles based on hydrophobically-modified sulfated chitosan as a carrier of doxorubicin.: Research demonstrates the potential of hydrophobically-modified sulfated chitosan micelles, incorporating lauric aldehyde, for improving the delivery of chemotherapeutic agents, particularly doxorubicin, enhancing drug stability and reducing side effects (Wang et al., 2012).

  • Biocompatibility of injectable chitosan-phospholipid implant systems.: Investigates the biocompatibility of chitosan-phospholipid injectable implants, where lauric aldehyde could play a role in modifying polymer matrices to enhance biocompatibility and drug release profiles, critical for medical implant technologies (De Souza et al., 2009).


Pittogrammi

Exclamation markEnvironment

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

213.8 °F - closed cup

Punto d’infiammabilità (°C)

101 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Certificati d'analisi (COA)

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Green odorants of grape cluster stem and their ability to cause a wine stemmy flavor.
Hashizume K & Samuta T.
Journal of Agricultural and Food Chemistry, 45(4), 1333-1337 (1997)
Analysis of carbonyl flavor constituents from grapefruit oil.
Moshonas MG.
Journal of Agricultural and Food Chemistry, 19(4), 769-770 (1971)
Markus A Keller et al.
Nature communications, 5, 4439-4439 (2014-07-23)
Mutations in the gene coding for membrane-bound fatty aldehyde dehydrogenase (FALDH) lead to toxic accumulation of lipid species and development of the Sjögren-Larsson Syndrome (SLS), a rare disorder characterized by skin defects and mental retardation. Here, we present the crystallographic
Tetyana Kobets et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 115, 228-243 (2018-03-20)
Genotoxicity of flavor and fragrance materials was assessed in Turkey Egg Genotoxicity Assay (TEGA) using 32P-nucleotide postlabeling (NPL) and comet assays to detect hepatic DNA adducts and strand breaks. Twenty materials having results in GADD45a-Gluc 'BlueScreen HC' genotoxicity assay, and
James Liu et al.
Journal of pharmaceutical sciences, 104(3), 1187-1196 (2015-01-13)
The objective of this study is to develop and compare several Sorafenib-loaded biocompatible nanoparticle models in order to optimize drug delivery and tumor cellular kill thereby improving the quality of Sorafenib-regimented chemotherapy. Sorafenib-loaded poly (lactic-co-glycolic) acid (PLGA), 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) liposomes

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