QBD11487

MAL-dPEG^®₂₄-Tris(-dPEG^®₂₄-Tris(m-dPEG^®₂₄)₃)₃

>95% (HPLC)

• Sinonimo/i: 9-arm mPEG 14K PEG₁₀₀₀-MAL, Branched Maleimide-PEG-m, Branched mPEG-maleimide, MAL-PEG₂₄-Tris(-PEG₂₄-Tris(m-PEG₂₄)₃)₃
• Formula empirica (notazione di Hill): C₇₀₄H₁₃₈₆N₁₈O₃₄₃
• Peso molecolare: 15592.45
• Codice UNSPSC: 12352106
• NACRES: NA.22

Proprietà

• Saggio: >95% (HPLC)
• Forma fisica: solid or viscous liquid
• Impiego in reazioni chimiche: reaction type: Pegylations
• Architettura del polimero: functionality: monofunctional
• Condizioni di spedizione: ambient
• Temperatura di conservazione: −20°C

Descrizione

Caratteristiche e vantaggi

MAL-dPEG₂₄-Tris (-dPEG₂₄-Tris (m-dPEG₂₄)₃)₃ is a sulfhydryl-reactive, multibranched, monodispersed PEG product. The product is built around tris. One arm terminates in a maleimide group that reacts selectively with free thiols in a click chemistry type of reaction. Nine branches terminate in methyl groups. The molecular weight of the product is 15,592 Daltons. The amphiphilic PEG imparts tremendous water solubility to conjugate molecules and expands their hydrodynamic volume sufficiently to eliminate the renal clearance of the conjugates. The end-to-end length of the dPEG spacer from the maleimido olefin to the terminal methyl group on each branch is 245 atoms, with an average distance of 171.2 Å.

Note legali

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681

dPEG is a registered trademark of Quanta BioDesign

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable