QBD10275

MAL-dPEG^®₈-acid

>95% (HPLC)

• Sinonimo/i: Carboxy-PEG-maleimide, Carboxy-PEG₈-maleimide, MAL-PEG₄₀₀-acid, MAL-PEG₈-COOH, MAL-PEG₈-acid
• Formula empirica (notazione di Hill): C₂₆H₄₄N₂O₁₃
• Peso molecolare: 592.63
• Numero MDL: MFCD13184956
• Codice UNSPSC: 12352106
• NACRES: NA.22

Proprietà

• Saggio: >95% (HPLC)
• Forma fisica: solid or viscous liquid
• Impiego in reazioni chimiche: reaction type: Pegylations
• Architettura del polimero: shape: linear; functionality: heterobifunctional
• Condizioni di spedizione: ambient
• Temperatura di conservazione: −20°C

Descrizione

Caratteristiche e vantaggi

MAL-dPEG₈-acid is a monodisperse crosslinker that joins sulfhydryl groups to free amines through a single molecular weight polyethylene glycol (PEG) chain of discrete length. The linker is 34 atoms and 38.8 Å long. The maleimidopropyl moiety reacts with sulfhydryl groups via a Michael addition reaction. The propionic acid terminus of the molecule reacts directly with free amines using EDC or another carbodiimide to form amide bonds. Alternatively, activation of the propionic acid group with N-hydroxysuccinimide (NHS), 2,3,5,6-tetrafluorophenol (TFP), or some other acylating agent permits amide bond formation under mild, controlled conditions.

Note legali

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681

dPEG is a registered trademark of Quanta BioDesign

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable