P8533

Tributylammonium pyrophosphate

• Sinonimo/i: N,N-dibutyl-1-butanamine diphosphate
• Numero CAS: 5975-18-8
• Numero MDL: MFCD00136019
• Codice UNSPSC: 12352116
• ID PubChem: 329820329
• NACRES: NA.22

Proprietà

• Stato: powder
• Livello qualitativo: 200
• Temperatura di conservazione: −20°C
• Stringa SMILE: OP(O)(=O)OP(O)(O)=O.CCCCN(CCCC)CCCC.CCCCN(CCCC)CCCC
• InChI: 1S/2C12H27N.H4O7P2/c2*1-4-7-10-13(11-8-5-2)12-9-6-3;1-8(2,3)7-9(4,5)6/h2*4-12H2,1-3H3;(H2,1,2,3)(H2,4,5,6); WRMXOVHLRUVREB-UHFFFAOYSA-N

Descrizione

Descrizione generale

Tributylammonium pyrophosphate is a phosphorylating reagent used in the synthesis of modified dNTPs (deoxynucleoside triphosphates) which are important building blocks for the generation of DNA, RNA, functionalized nucleic acids.

Applicazioni

Reactant for:

• Enzymic synthesis of 3′-deoxy-apio-nucleic acid duplexes
• Synthesis of deoxynucleoside S-methylphosphonic acids
• Preparation of fluorescent non-nucleotide ATP analog N-methylanthraniloylamideethyl triphosphate

Tributylammonium pyrophosphate used as a phosphorylating reagent:

• In the synthesis of S′-deoxy-S′-methylphosphonic acid diphosphate along with 1, 1′-carbonyl diimidazole.
• In the synthesis of gram-scale level base-modified ribonucleoside-5′-O-triphosphates.
• In one-pot chemical synthesis of 2′-deoxynucleoside-5′-triphosphates with better protection.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)