P2066
Poly(D,L-lactide-co-glycolide)
lactide:glycolide 65:35, Mw 40,000-75,000
Sinonimo/i:
Lactel® B6001-1, PLGA
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About This Item
Formula condensata:
[C3H4O2]x[C2H2O2]y
Numero MDL:
Codice UNSPSC:
12162002
ID PubChem:
NACRES:
NA.23
Prodotti consigliati
Forma fisica
pellets
Livello qualitativo
Rapporto d’alimentazione
lactide:glycolide 65:35
PM
Mw 40,000-75,000
Temperatura di conservazione
−20°C
Stringa SMILE
OCC(O)=O.CC(O)C(O)=O
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Categorie correlate
Applicazioni
- Inhaled Macrophage Apoptotic Bodies-Engineered Microparticle Enabling Construction of Pro-Regenerative Microenvironment to Fight Hypoxic Lung Injury in Mice.: This study demonstrates the use of Poly(ᴅ,ʟ-lactide-co-glycolide) (PLGA) in engineering microparticles that promote lung tissue regeneration in hypoxic conditions, highlighting its potential in developing advanced therapeutic strategies for respiratory injuries (Liu et al., 2024).
- Engineered nanoparticles promote cardiac tropism of AAV vectors.: The research explores the role of PLGA nanoparticles in enhancing the targeting efficiency of AAV vectors to cardiac tissues, showcasing its application in gene therapy and cardiovascular disease treatment (Switala et al., 2024).
- Drug-loaded adhesive microparticles for biofilm prevention on oral surfaces.: This article reports the development of drug-loaded PLGA microparticles designed to prevent biofilm formation on oral surfaces, demonstrating the polymer′s utility in dental applications and biofilm-associated infections (Oh et al., 2024).
- Dual-layer conduit containing VEGF-A - Transfected Schwann cells promotes peripheral nerve regeneration via angiogenesis.: PLGA-based dual-layer conduits are utilized to support nerve regeneration by enhancing angiogenesis, indicating its importance in neuroregenerative medicine and peripheral nerve injury treatments (Huang et al., 2024).
- Application of Doxorubicin-loaded PLGA nanoparticles targeting both tumor cells and cancer-associated fibroblasts on 3D human skin equivalents mimicking melanoma and cutaneous squamous cell carcinoma.: The study highlights the dual-targeting capability of PLGA nanoparticles in delivering chemotherapy drugs to both tumor cells and the surrounding supportive stroma, emphasizing its role in advanced cancer therapies (He et al., 2024).
Caratteristiche e vantaggi
Controlled release of bioactive agents, sutures and bioabsorbable implantable devices.
Stato fisico
Biocompatible, biodegradable polymer.
Note legali
Lactel is a registered trademark of Evonik Corp
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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A series of biodegradable low molecular weight PLGA-PEG-PLGA tri-block copolymers have been synthesized in powder form. The anti-tuberculosis drug Isoniazid (INH) loaded polymeric core-shell nanoparticles (CSNPs) have been prepared by sonication followed by water-in-oil-in-water (w/o/w) double emulsification technique. The nanoparticles
Articoli
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Protocolli
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