934305

Pomalidomide-PEG1-C2-amine HCl

≥95.0%

• Sinonimo/i: 4-[[2-(2-Aminoethoxy)ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride
• Formula empirica (notazione di Hill): C₁₇H₂₀N₄O₅ · xHCl
• Numero CAS: 2154342-56-8
• Peso molecolare: 360.36 (free base basis)
• Numero MDL: MFCD32666562
• Codice UNSPSC: 12352116
• NACRES: NA.21

Proprietà

• ligand: pomalidomide
• Livello qualitativo: 100
• Saggio: ≥95.0%
• Stato: powder or crystals
• Colore: faint yellow to dark yellow
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: Cl.O=C1NC(=O)C(N2C(=O)C=3C=CC=C(NCCOCCN)C3C2=O)CC1
• InChI: 1S/C17H20N4O5.ClH/c18-6-8-26-9-7-19-11-3-1-2-10-14(11)17(25)21(16(10)24)12-4-5-13(22)20-15(12)23;/h1-3,12,19H,4-9,18H2,(H,20,22,23);1H; LQYLHZFKGOZTOH-UHFFFAOYSA-N

Descrizione

Applicazioni

Technology Spotlight:

Degrader Building Blocks for Targeted Protein Degradation

Protein Degrader Building Blocks

Altre note

Targeted Protein Degradation by Small Molecules

Destruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O′PROTAC): Effective Targeting of LEF1 and ERG

Small-Molecule PROTACS: New Approaches to Protein Degradation

Targeted Protein Degradation: from Chemical Biology to Drug Discovery

Impact of linker length on the activity of PROTACs

Note legali

PROTAC^® is a registered trademark of Arvinas Operations, Inc., and is used under license.

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

Informazioni sulla sicurezza

• Pittogrammi: GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H360D
• Consigli di prudenza: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Classi di pericolo: Repr. 1B
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable