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Documenti fondamentali

913286

Sigma-Aldrich

Methoxypolyethylene epoxide

PEG average Mn 750

Sinonimo/i:

Epoxide PEG, mPEG-epoxide

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About This Item

Formula condensata:
C3H5O2(C2H4O)nCH3
Codice UNSPSC:
43211915
NACRES:
NA.23

Stato

semisolid

PM

PEG average Mn 750
average Mn 750 (by NMR)

Colore

white to off-white

Estremità Ω

(epoxide)

Estremità α

methoxy

Architettura del polimero

shape: linear
functionality: monofunctional

Temperatura di conservazione

2-8°C

Applicazioni

Epoxide functionalized PEG can be covalently bonded to polymers and biopolymers by epoxide ring-opening reactions. As a surface coating, PEGylated surfaces prevent cell adhesion by entropically driven steric repulsion. For drug delivery, PEGylation increases the hydrophilicity of the drug carrier.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Rajesh Kumar Kainthan et al.
Biomacromolecules, 9(3), 886-895 (2008-02-06)
This paper discusses the binding and release properties of hydrophobically modified hyperbranched polyglycerol-polyethylene glycol copolymers that were originally developed as human serum albumin (HSA) substitutes. Their unimolecular micellar nature in aqueous solution has been proven by size measurements and other
Mohamed H Ramadan et al.
Langmuir : the ACS journal of surfaces and colloids, 30(25), 7485-7495 (2014-06-04)
We report a thermoresponsive chemical modification strategy of hyaluronic acid (HA) for coating onto a broad range of biomaterials without relying on chemical functionalization of the surface. Poly(di(ethylene glycol) methyl ether methacrylate) (PMEO2MA), a polymer with a lower critical solution
Simone M Haag et al.
Nature, 559(7713), 269-273 (2018-07-06)
Aberrant activation of innate immune pathways is associated with a variety of diseases. Progress in understanding the molecular mechanisms of innate immune pathways has led to the promise of targeted therapeutic approaches, but the development of drugs that act specifically
Jameel Ahmad Khan et al.
Biomacromolecules, 7(5), 1386-1388 (2006-05-09)
Recent advances in understanding biological systems have proven that RNA is not merely the carrier of genetic information, but also a key molecule in regulation of gene expression and other crucial metabolic processes. Therefore, it is being considered as an

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