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713783

Sigma-Aldrich

O,O′-Bis[2-(N-Succinimidyl-succinylamino)ethyl]polyethylene glycol

2,000

Sinonimo/i:

Polyethylene glycol, α,ω-Bis-NHS-PEG, Di(N-succinimidyl) PEG-diacid, PEG-bis(N-succinimidyl succinate)

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About This Item

Numero CAS:
186020-53-1
Numero MDL:
MFCD03792507
Codice UNSPSC:
12162002
NACRES:
NA.22

Livello qualitativo

100

Stato

powder

PM

average Mn 2,000

Impiego in reazioni chimiche

reagent type: cross-linking reagent

Estremità Ω

NHS ester

Estremità α

NHS ester

Temperatura di conservazione

−20°C

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Categorie correlate

Descrizione generale

O,O′-Bis[2-(N-Succinimidyl-succinylamino)ethyl]polyethylene glycol (NHS-PEG-NHS) is a cross-linking reagent.

Applicazioni

O,O′-Bis[2-(N-Succinimidyl-succinylamino)ethyl]polyethylene glycol (NHS-PEG-NHS) is suitable reagent used in the covalent conjugation of peanut agglutinin and anticarcinoembryonic antigen antibodies (αCEA) tumor-targeting ligands to near-infrared (NIR)fluorescent superparamagnetic iron oxide (IO)- human serum albumin (HSA) nanoparticles. It is suitable reagent used in the synthesis of novel series of mesoporous silica nanoparticles with different pore sizes, useful for high loading and controlled release of short oligonucleotides.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
BCCG4340
BCCC7724
BCCC2725
BCCB7092
BCCB0639

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Jixi Zhang et al.
Dalton transactions (Cambridge, England : 2003), 43(10), 4115-4126 (2014-01-25)
Aimed at high loading and controlled release of oligonucleotides with short sequences of base-pairs, a novel series of mesoporous silica nanoparticles with three different pore sizes (3.5-5.0 nm) but the same cleavable surface linkers (MSN-Linker-Cys) were synthesized. The small particle
Enav Corem-Salkmon et al.
International journal of nanomedicine, 7, 5517-5527 (2012-11-01)
Colon cancer is one of the major causes of death in the Western world. Early detection significantly improves long-term survival for patients with the disease. Near- infrared (NIR) fluorescent nanoparticles hold great promise as contrast agents for tumor detection. NIR

Articoli

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Injectable Hydrogels for Cell Delivery and Tissue Regeneration

The use of hydrogel-based biomaterials for the delivery and recruitment of cells to promote tissue regeneration in the body is of growing interest. This article discussed the application of hydrogels in cell delivery and tissue regeneration.

Global Trade Item Number

SKUGTIN
713783-500MG4061833228920

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