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Key Documents

672130

Sigma-Aldrich

O-(2-Aminoethyl)polyethylene glycol

Mp 5,000

Sinonimo/i:

Polyethylene glycol, Aminopolyethylene glycol 5,000

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About This Item

Formula condensata:
NH2(CH2CH2O)nH
Numero CAS:
Numero MDL:
Codice UNSPSC:
12352200
ID PubChem:
NACRES:
NA.22

PM

Mp 5,000

Livello qualitativo

Estremità Ω

hydroxyl

Estremità α

amine

Applicazioni

O-(2-Aminoethyl)polyethylene glycol (PEG-NH2) can be used:
  • As a capping ligand in the synthesis of water-dispersible and non-toxic nanocrystals (ZnS:Mn) for the development of environment friendly materials.
  • In the surface modification of magnetic nanoparticles (MNPs) for a variety of biomedical applications.

Bottomless glass bottle. Contents are inside inserted fused cone.
Reactant for:
  • Preparation of pH responsive self-healing hydrogels formed by boronate-catechol complexation
  • Preparation of core-clickable PEG-branch-azide bivalent-bottle-brush polymers by ROMP
  • Preparation of drug-loaded bivalent-bottle-brush polymers by graft-through ROMP

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Potential of magnetic nanoparticles for targeted drug delivery
Yang H-W, et al.
Nanotechnology, Science and Applications, 5(4), 73-73 (2012)
Syntheses of Biologically Non-Toxic ZnS: Mn Nanocrystals by Surface Capping with O-(2-aminoethyl) polyethylene Glycol and O-(2-carboxyethyl) polyethylene Glycol Molecules
Kong H-Y, et al.
Bull. Korean Chem. Soc., 34(4), 1181-1187 (2013)

Articoli

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a threedimensional (3D) fashion is a challenging requirement in the field of tissue engineering and regenerative medicine.

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