07964
Methoxypolyethylene glycol amine
750
Sinonimo/i:
mPEG-NH2, O-(2-Aminoethyl)-O′-methylpolyethylene glycol, Aminopolyethylene glycol monomethyl ether, Methoxypolyoxyethylene amine
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About This Item
Prodotti consigliati
Livello qualitativo
Forma fisica
solid
Colore
white to yellow
InChI
1S/C3H9NO/c1-5-3-2-4/h2-4H2,1H3
ASUDFOJKTJLAIK-UHFFFAOYSA-N
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Applicazioni
Methoxypolyethylene glycol amine can:
- Form dendritic micelles to enhance the solubility of hydrophobic compounds.
- Conjugate with an anticancer drug methotrexate (MTX) to form MTX-PEG with potential application as drug carriers.
- Couple with polyethylenimine (PEI) to form graft copolymers which can be used as nonviral gene vectors.
Altre note
Oligomer used to prepare PEG-ylated conjugates having the advantage of reduced immunogenicity and increased serum half life
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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I clienti hanno visto anche
Effect of polyethylene glycol on gene delivery of polyethylenimine.
Biological & Pharmaceutical Bulletin, 26(4), 492-500 (2003)
Bioconjugate chemistry, 3(4), 295-301 (1992-07-01)
Adriamycin, a hydrophobic anticancer drug, was conjugated with poly(ethylene oxide)-poly(aspartic acid) block copolymers composed of various lengths of each block copolymer segment ranging from 1000 to 12,000 in molecular weight and from 10 to 80 units, respectively. Conjugation was achieved
Polyethylene Glycol Conjugates of Methotrexate Varying in Their Molecular Weight from MW 750 to MW 40000: Synthesis, Characterization, and Structure- Activity Relationships in Vitro and in Vivo.
Bioconjugate Chemistry, 13(4), 773-785 (2002)
Synthetic Communications, 22, 2417-2417 (1992)
Polyethylene glycol-polyamidoamine dendritic micelle as solubility enhancer and the effect of the length of polyethylene glycol arms on the solubility of pyrene in water.
Journal of Colloid and Interface Science, 273(1), 148-154 (2004)
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