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Key Documents

Altri documenti

47618

Sigma-Aldrich

Fmoc-Asp(OtBu)-OH

≥98.0% (HPLC), for peptide synthesis

Sinonimo/i:

Fmoc-L-aspartic acid 4-tert-butyl ester

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About This Item

Formula empirica (notazione di Hill):
C23H25NO6
Numero CAS:
71989-14-5
Peso molecolare:
411.45
Beilstein:
3635671
Numero CE:
276-251-7
Numero MDL:
MFCD00037131
Codice UNSPSC:
12352209
eCl@ss:
32160406
ID PubChem:
57651040
NACRES:
NA.26

product name

Fmoc-Asp(OtBu)-OH, ≥98.0% (HPLC)

Saggio

≥98.0% (HPLC)

Forma fisica

powder

Attività ottica

[α]20/D −24±2°, c = 1% in DMF

Impiego in reazioni chimiche

reaction type: Fmoc solid-phase peptide synthesis

Punto di fusione

148-150 °C (dec.)

applicazioni

peptide synthesis

Gruppo funzionale

Fmoc

Temperatura di conservazione

2-8°C

Stringa SMILE

CC(C)(C)OC(=O)C[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O

InChI

1S/C23H25NO6/c1-23(2,3)30-20(25)12-19(21(26)27)24-22(28)29-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,24,28)(H,26,27)/t19-/m0/s1
FODJWPHPWBKDON-IBGZPJMESA-N

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Categorie correlate

Descrizione generale

Fmoc-Asp(OtBu)-OH also known as Fmoc-L-aspartic acid 4-tert-butyl ester, is a Fmoc protected amino acid, used in solid phase peptide synthesis.

Applicazioni

Fmoc-Asp(OtBu)-OH is used to prevent the formation of aspartimide by-products in Fmoc solid phase peptide synthesis.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Sigma-Aldrich

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Fengyang Xu et al.
ACS applied materials & interfaces, 8(44), 29906-29914 (2016-10-21)
In this work, we reported the generation of a novel supramolecular hydrogelator from a peptide derivative which consisted of a structural motif (e.g., Fc-FF) for supramolecular self-assembly and a functional moiety (e.g., RGD) for integrin binding. Following self-assembly in water
Jisi Zhao et al.
Molecules (Basel, Switzerland), 24(4) (2019-03-03)
Photodynamic therapy (PDT) is an established therapeutic modality for the management of cancers. Conjugation with tumor-specific small molecule ligands (e.g., short peptides or peptidomimetics) could increase the tumor targeting of PDT agents, which is very important for improving the outcome
R Ashton Lavoie et al.
International journal of molecular sciences, 20(7) (2019-04-11)
The growing integration of quality-by-design (QbD) concepts in biomanufacturing calls for a detailed and quantitative knowledge of the profile of impurities and their impact on the product safety and efficacy. Particularly valuable is the determination of the residual level of
R Ashton Lavoie et al.
Biotechnology and bioengineering, 117(2), 438-452 (2019-10-28)
The clearance of host cell proteins (HCPs) is of crucial importance in biomanufacturing, given their diversity in composition, structure, abundance, and occasional structural homology with the product. The current approach to HCP clearance in the manufacturing of monoclonal antibodies (mAbs)
Stefan Eissler et al.
Journal of peptide science : an official publication of the European Peptide Society, 23(10), 757-762 (2017-06-22)
In solid-phase peptide synthesis, the nominal batch size is calculated using the starting resin substitution and the mass of the starting resin. The starting resin substitution constitutes the basis for the calculation of a whole set of important process parameters
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