422231
4-(Trifluoromethoxy)benzamidoxime
97%
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About This Item
Formula condensata:
CF3OC6H4C(=NOH)NH2
Numero CAS:
Peso molecolare:
220.15
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22
Prodotti consigliati
Livello qualitativo
Saggio
97%
Punto di fusione
113-115 °C (lit.)
Gruppo funzionale
amine
fluoro
oxime
Stringa SMILE
N\C(=N/O)c1ccc(OC(F)(F)F)cc1
InChI
1S/C8H7F3N2O2/c9-8(10,11)15-6-3-1-5(2-4-6)7(12)13-14/h1-4,14H,(H2,12,13)
COHKFOZYLCDVRK-UHFFFAOYSA-N
Descrizione generale
4-(Trifluoromethoxy)benzamidoxime (4-TFMBAO) is a benzamidoxime (BAO) derivative containing amidoxime functional group. Its density and freezing point have been determined.
Applicazioni
4-(Trifluoromethoxy)benzamidoxime (4-TFMBAO) is suitable reactant in the fluorescence (FL) deriving reaction, one of the widely-used methodology specifically used to quantify uracil. It may be used as a reactant in the synthesis of oxadiazoles. It may also be used a fluorogenic agent in the quantification of orotic acid by spectrofluorometric method in human biological specimens.
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Organi bersaglio
Respiratory system
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
dust mask type N95 (US), Eyeshields, Gloves
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Sensitive and Selective Determination of Orotic Acid in Biological Specimens Using a Novel Fluorogenic Reaction.
Yin S, et al.
Journal of Fluorescence, 25(4), 1005-1011 (2015)
Thomas E Barta et al.
Bioorganic & medicinal chemistry letters, 21(10), 2820-2822 (2011-04-22)
Seeking compounds preferentially potent and selective for MMP-13, we reported in the preceding Letter on a series of hydroxamic acids with a flexible benzamide tail groups.(1a) Here, we replace the amide moiety with non-hydrolyzable heterocycles in an effort to improve
Yaws CL.
The Yaws Handbook of Physical Properties for Hydrocarbons and Chemicals, 185-185 (2015)
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Analytica chimica acta, 674(2), 234-238 (2010-08-04)
Facile and specific methods to quantify a nucleobase in biological samples are of great importance for diagnosing disorders in nucleic acid metabolism. In the present study, a novel fluorogenic reaction specific for uracil has been developed. The reaction was carried
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