394882

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide

>97%

• Sinonimo/i: MTBSTFA
• Formula condensata: CF₃CON(CH₃)Si(CH₃)₂C(CH₃)₃
• Numero CAS: 77377-52-7
• Peso molecolare: 241.33
• Beilstein: 3606546
• Numero MDL: MFCD00009671
• Codice UNSPSC: 12352001
• ID PubChem: 24864624
• NACRES: NA.22

Proprietà

• Grado: derivatization grade
• Livello qualitativo: 200
• Saggio: >97%
• Stato: liquid
• Indice di rifrazione: n20/D 1.402 (lit.)
• P. ebollizione: 172-175 °C (lit.)
• Densità: 1.036 g/mL at 25 °C (lit.)
• Gruppo funzionale: amine; fluoro
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: CN(C(=O)C(F)(F)F)[Si](C)(C)C(C)(C)C
• InChI: 1S/C9H18F3NOSi/c1-8(2,3)15(5,6)13(4)7(14)9(10,11)12/h1-6H3; QRKUHYFDBWGLHJ-UHFFFAOYSA-N

Descrizione

Descrizione generale

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide is a highly reactive silylating reagent commonly used for silyation of carboxylic acids, alcohols, amines, and thiols. It is also used as a protection, deprotection reagent.

Applicazioni

N-tert-butyldimethylsilyl-N-methyltrifluoroacetamide (MTBSTFA) can be used:

• As a derivatizing agent in the GC-MS analysis of hydroxylated fluorenes and in the GC analysis of amino acids.
• As an efficient silylating agent for different alcohols, thiols, phenols, carboxylic acids, amines, and amides.
• To functionalize multi-walled carbon nanotubes (MWCNTs) with polar groups.

MTBSTFA is reportedly much less moisture-sensitive than other silylating reagents used for GLC derivatization.

Informazioni sulla sicurezza

• Pittogrammi: GHS02
• Avvertenze: Warning
• Indicazioni di pericolo: H226
• Consigli di prudenza: P210 - P233 - P240 - P241 - P242 - P243
• Classi di pericolo: Flam. Liq. 3
• Codice della classe di stoccaggio: 3 - Flammable liquids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): 113.0 °F - closed cup
• Punto d’infiammabilità (°C): 45 °C - closed cup
• Dispositivi di protezione individuale: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter