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Key Documents

392650

Sigma-Aldrich

2,2,5,5-Tetramethyl-3-pyrroline-3-carboxamide

99%

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About This Item

Formula empirica (notazione di Hill):
C9H16N2O
Numero CAS:
Peso molecolare:
168.24
Numero CE:
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22

Livello qualitativo

Saggio

99%

Punto di fusione

180-182 °C (lit.)

Stringa SMILE

CC1(C)NC(C)(C)C(=C1)C(N)=O

InChI

1S/C9H16N2O/c1-8(2)5-6(7(10)12)9(3,4)11-8/h5,11H,1-4H3,(H2,10,12)
ACFYUJLIWIDSFM-UHFFFAOYSA-N

Categorie correlate

Descrizione generale

2,2,5,5-Tetramethyl-3-pyrroline-3-carboxamide is a carboxamide of a hydrogenated pyrrole derivative. It is a sterically hindered amino compound having amino alkyl side chain. The antiarrhythmic activity of some of the derivatives of 2,2,5,5-tetramethyl-3-pyrroline-3-carboxamide have been evaluated.

Applicazioni

2,2,5,5-Tetramethyl-3-pyrroline-3-carboxamide may be used in the synthesis of 2,2,5,5-tetramethyl-3-pyrrolidinecarboxamide and 3-carbamoyl-2,2,5,5-tetramethyl-3-pyrrolin-1-yloxy free radical.

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


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Nitroxide free radicals in the hydrogenated pyrrole series.
Rozantsev EG, et al.
Russian Chemical Bulletin, 15(4), 638-641 (1966)
O H Hankovszky et al.
Journal of medicinal chemistry, 29(7), 1138-1152 (1986-07-01)
N-(omega-Aminoalkyl)-2,2,5,5-tetramethyl-3-pyrroline- or -pyrrolidine-3-carboxamides were acylated on the primary amino group of the side chain by means of reactive acid derivatives (acid chlorides, activated esters, phthalic anhydrides, phthalimide, 2-alkyl-4H-3,1-benzoxazin-4-ones) or they were alkylated by forming the Schiff bases and subsequent sodium
Keisuke Nakamura et al.
Journal of clinical biochemistry and nutrition, 49(2), 87-95 (2011-10-08)
The aim of the present study is to compare different analytical methods for singlet oxygen and to discuss an appropriate way to evaluate the yield of singlet oxygen photogenerated from photosensitizers. Singlet oxygen photogenerated from rose bengal was evaluated by
Yusuke Katsuda et al.
PloS one, 10(8), e0134704-e0134704 (2015-08-11)
Cytoprotective effects of short-term treatment with grape seed extract (GSE) upon human gingival fibroblasts (hGFs) were evaluated in relation to its antioxidant properties and compared with those of a water-soluble analog of vitamin E: trolox (Tx). GSE and Tx showed

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