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Merck
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272264

Sigma-Aldrich

1-(3-Aminopropyl)imidazole

≥97%

Sinonimo/i:

1-(3-Aminopropanyl)imidazole, 3-(1-Imidazolyl)propylamine, 3-(1H-Imidazol-1-yl)propylamine, 3-(Imidazol-1-yl)propylamine, N-(3-Aminopropyl)imidazole, N-[3-(1H-Imidazol-1-yl)propyl]amine

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About This Item

Formula empirica (notazione di Hill):
C6H11N3
Numero CAS:
5036-48-6
Peso molecolare:
125.17
Numero CE:
225-730-9
Numero MDL:
MFCD00009819
Codice UNSPSC:
12352005
ID PubChem:
24856463
NACRES:
NA.22

Saggio

≥97%

Forma fisica

liquid

Indice di rifrazione

n20/D 1.519 (lit.)

Densità

1.049 g/mL at 25 °C (lit.)

Stringa SMILE

NCCCn1ccnc1

InChI

1S/C6H11N3/c7-2-1-4-9-5-3-8-6-9/h3,5-6H,1-2,4,7H2
KDHWOCLBMVSZPG-UHFFFAOYSA-N

Applicazioni

1-(3-Aminopropyl)imidazole was used in the synthesis of pH-sensitive polyaspartamide derivatives. It was also used in the preparation of pH-sensitive amphiphilic polymers with different degrees of octaceylamine (C18) substitution by graft reaction.

Pittogrammi

CorrosionExclamation mark
GHS05,GHS07

Avvertenze

Danger

Indicazioni di pericolo

H302,H314,H412

Classi di pericolo

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1B

Codice della classe di stoccaggio

8A - Combustible corrosive hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

309.2 °F

Punto d’infiammabilità (°C)

154 °C

Dispositivi di protezione individuale

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Certificati d'analisi (COA)

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Sigma-Aldrich

CDS007822

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Combination therapy is considered to be a promising strategy for improving the therapeutic efficiency of cancer treatment. In this study, an on-demand pH-sensitive nanocluster (NC) system was prepared by the encapsulation of gold nanorods (AuNR) and doxorubicin (DOX) by a
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AAPS PharmSciTech (2018-06-20)
The complex design of multifunctional nanomedicine is beneficial to overcome the multiple biological barriers of drug delivery, but it also presents additional hurdles to clinical translation (e.g., scaling-up and quality control). To address this dilemma, we employed a simple imidazole-bearing
Kwangwon Seo et al.
Macromolecular bioscience, 6(9), 758-766 (2006-09-13)
New pH-sensitive polyaspartamide derivatives were synthesized by grafting 1-(3-aminopropyl)imidazole and/or O-(2-aminoethyl)-O'-methylpoly(ethylene glycol) 5000 on polysuccinimide for application in intracellular drug delivery systems. The DS of 1-(3-aminopropyl)imidazole was adjusted by the feed molar ratio, and the structure of the prepared polymer
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