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270873

Sigma-Aldrich

2-Hydroxyquinoline

98%

Sinonimo/i:

2-Quinolinol, Carbostyril

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About This Item

Formula empirica (notazione di Hill):
C9H7NO
Numero CAS:
59-31-4
Peso molecolare:
145.16
Numero CE:
200-420-6
Numero MDL:
MFCD00006743
Codice UNSPSC:
12352100
ID PubChem:
24856409
NACRES:
NA.22

Livello qualitativo

100

Saggio

98%

Stato

crystals

Punto di fusione

198-199 °C (lit.)

Solubilità

alcohol: soluble(lit.)
diethyl ether: soluble(lit.)
dilute HCl: soluble(lit.)
water: slightly soluble (1 g/950mL)(lit.)

Stringa SMILE

Oc1ccc2ccccc2n1

InChI

1S/C9H7NO/c11-9-6-5-7-3-1-2-4-8(7)10-9/h1-6H,(H,10,11)
LISFMEBWQUVKPJ-UHFFFAOYSA-N

Descrizione generale

2-Hydroxyquinoline is a specific inhibitor of plaque paraoxonase1 (PON1).

Applicazioni

2-Hydroxyquinoline was used to obtain the design of the platinum(IV) complexes with intense bands shifted towards longer wavelengths. The Pt(IV) complexes are inert stable prodrugs that were photoactivated to produce Pt(II) species with promising anticancer activity.

Pittogrammi

CorrosionExclamation mark
GHS05,GHS07

Avvertenze

Danger

Indicazioni di pericolo

H302,H315,H318,H335

Classi di pericolo

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

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Certificati d'analisi (COA)

Lot/Batch Number
15529BQ
13831JZ
04824PT
18904PS
17608KO

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2-Hydroxyquinoline-4-carboxylic acid 97%

Sigma-Aldrich

674869

2-Hydroxyquinoline-4-carboxylic acid

2,4-Quinolinediol 97%

Sigma-Aldrich

Q1336

2,4-Quinolinediol

2-Hydroxy-4-methylquinoline 97%

Sigma-Aldrich

H43601

2-Hydroxy-4-methylquinoline

Hui-Chung Tai et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 18(34), 10630-10642 (2012-07-19)
Diazido Pt(IV) complexes are inert stable prodrugs that can be photoactivated to produce Pt(II) species with promising anticancer activity. Our studies of the photochemistry of Pt(IV) complexes, [Pt(X)(2) (Y)(2) (Z)(2) ](0/-1) (X=N-ligands (NH(3) , pyridine, etc.)/S(CH(3) )(2) /H(-) , Y=(pseudo)halogen
Kaitlyn M Ferguson et al.
Frontiers in microbiology, 9, 2190-2190 (2018-10-05)
Objective: The intestinal concentrations of antimicrobial drugs that select for resistance in fecal bacteria of cattle are poorly understood. Our objective was to associate active drug concentrations in the intestine of steers with changes in the resistance profile and composition
Alexander J Bones et al.
Experimental parasitology, 196, 28-37 (2018-12-07)
Cryptosporidium is a genus of single celled parasites capable of infecting a wide range of animals including humans. Cryptosporidium species are members of the phylum apicomplexa, which includes well-known genera such as Plasmodium and Toxoplasma. Cryptosporidium parasites cause a severe
Shirin Biglari et al.
Microbial drug resistance (Larchmont, N.Y.), 23(5), 545-555 (2016-11-18)
Multidrug-resistant (MDR) Acinetobacter baumannii has increasingly emerged as an important nosocomial pathogen. The aim of this study was to determine the resistance profiles and genetic diversity in A. baumannii clinical isolates in a tertiary medical center in Malaysia. The minimum
Antonios Keirouz et al.
Journal of nanobiotechnology, 18(1), 51-51 (2020-03-20)
The state-of-the-art hernia meshes, used in hospitals for hernia repair, are predominantly polymeric textile-based constructs that present high mechanical strength, but lack antimicrobial properties. Consequently, preventing bacterial colonization of implanted prosthetic meshes is of major clinical relevance for patients undergoing
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