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122262

Sigma-Aldrich

N,N,N′,N′-Tetrakis(2-Hydroxypropyl)ethylenediamine

98%

Sinonimo/i:

Edetol, Entprol, (Ethylenedinitrilo)tetra-2-propanol, Quadrol®

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About This Item

Formula condensata:
[CH3CH(OH)CH2]2NCH2CH2N[CH2CH(OH)CH3]2
Numero CAS:
Peso molecolare:
292.41
Beilstein:
1781143
Numero CE:
Numero MDL:
Codice UNSPSC:
12162002
ID PubChem:
NACRES:
NA.23

Tensione di vapore

1 mmHg ( 20 °C)

Saggio

98%

Indice di rifrazione

n20/D 1.4812 (lit.)

P. ebollizione

175-181 °C/0.8 mmHg (lit.)

Densità

1.013 g/mL at 25 °C (lit.)

Stringa SMILE

CC(O)CN(CCN(CC(C)O)CC(C)O)CC(C)O

InChI

1S/C14H32N2O4/c1-11(17)7-15(8-12(2)18)5-6-16(9-13(3)19)10-14(4)20/h11-14,17-20H,5-10H2,1-4H3
NSOXQYCFHDMMGV-UHFFFAOYSA-N

Descrizione generale

N,N,N′,N′-Tetrakis(2-Hydroxypropyl)ethylenediamine (also known as Quadrol) is an ethylenediamine based monomer used in the production of polyurethane coatings, adhesives, cosmetics and personal care products. It can act as a chelating agent, due to the presence of its four hydroxyl groups, and a crosslinking agent, due to its two amino groups. It is widely used as a building block for polymers and copolymers, particularly those that are designed for use in UV-cross linkable polyurethane polymers, dendritic amino polymers, conducting polymers, inks, and coatings. Additionally, Quadrol is used in the production of resins, as well as in the manufacture of surfactants, plasticizers, and other chemical products.

Applicazioni

N,N,N′,N′-Tetrakis(2-Hydroxypropyl)ethylenediamine can be used as:
  • A monomer in the synthesis of covalently cross-linked and amorphous shape memory polyurethane (SMPU) foams that are used in biomedical applications, which includes SMPU actuators for treating ischemic stroke, thrombus removal activated by laser light, self-deployable SMP neuronal electrodes, vascular stents, sutures in microsurgery, ocular implants, bandages, cell manipulation, and cell therapy.
  • A precursor in the preparation of self-healing CFRPs (carbon fiber reinforced polymer) which are thermally responsive with excellent mechanical properties.
  • A crosslinking agent to create a hydrogel that is biocompatible and supports the growth of neural cells. Hydrogels are specifically designed to mimic the properties of the extracellular matrix (ECM), in promoting cell proliferation. The purpose of the hydrogel in this context is to act as an extracellular matrix (ECM) substitute, providing a supportive environment for cell growth and guiding cell adhesion and outgrowth. This study investigates the potential of the peptide-modified channels to facilitate neural tissue engineering and enhance cell proliferation within the hydrogel-based scaffold.

Note legali

Quadrol is a registered trademark of BASF Corporation

Pittogrammi

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Avvertenze

Warning

Indicazioni di pericolo

Consigli di prudenza

Classi di pericolo

Eye Irrit. 2

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

411.8 °F - closed cup

Punto d’infiammabilità (°C)

211 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves


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Ona Gyliene et al.
Journal of hazardous materials, 175(1-3), 452-459 (2009-11-10)
Decontamination of solutions containing Cu(II) complexes with tartrate, glycine and quadrol (N,N,N'N'-tetrakis(2-hydroxypropyl)ethylenediamine) using metallic iron depends on pH and proceeds best in mildly acidic solutions. Cu(II) is completely removed from all solutions containing the ligands investigated. The degree of ligand
Gökhan Orhan et al.
Journal of hazardous materials, 112(3), 261-267 (2004-08-11)
An electrochemical method was applied for the recovery of copper both from the spent solutions and from the rinse waters of electroless copper plating baths, containing copper sulfate, formaldehyde, quadrol, and NaOH. Experiments were conducted in a rotating packed cell
M V Bhide et al.
Journal of immunopharmacology, 7(3), 303-312 (1985-01-01)
Mouse peritoneal macrophages, when exposed to Quadrol [N,N,N',N'-tetrakis(2-hydroxypropyl)ethylenediamine] in vitro, show a dose dependent enhanced spreading over a four-hour period. In vitro Quadrol induced phagocytosis of polystyrene beads was found to be time and concentration dependent. The rate and extent

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