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Merck

TPO

thyroid peroxidase

Sinonimi:
MSA, TDH2A, TPX
Specie:
ID UniProtKB:
ID gene:
  • Human(7173) Summary: This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]
  • Mouse(22018) thyroid peroxidase
  • Rat(54314) thyroid peroxidase
  • cow(525013) thyroid peroxidase
  • naked mole-rat(101704548) thyroid peroxidase
  • domestic guinea pig(100723704) thyroid peroxidase
  • chicken(776120) thyroid peroxidase
  • domestic cat(101098706) thyroid peroxidase
  • dog(403521) thyroid peroxidase

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ELISA

N° Catalogo
Descrizione
Specie
Human TPO / Thyroid Peroxidase ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-TPO antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunohistochemistry

western blot
Anti-TPO (Thyroid Peroxidase) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM368, purified immunoglobulin,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Anti-TPO antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-TPO antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot
Anti-Thyroid Peroxidase Antibody, clone 3C4A4, Rabbit Monoclonal, ,
Reattività con
human, rat
Applicazione
immunohistochemistry

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
Methimazole, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Methimazole, analytical standard,
Specie
human
Thiamazole, European Pharmacopoeia (EP) Reference Standard,
Specie
human
Methimazole, VETRANAL®, analytical standard,
Specie
human
2-Mercapto-1-methylimidazole, ≥99%,
Specie
human

Proteins

N° Catalogo
Descrizione
Specie
Thrombopoietin, TPO (Thrombopoietin, Mpl-ligand, MGDF) stimulates the proliferation & maturation of megakaryocytes & promotes increased circulating levels of platelets in vivo.,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human TPO,
Specie
human