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Merck

PDE1B

phosphodiesterase 1B, calmodulin-dependent

Sinonimi:
PDE1B1, PDES1B
Specie:
ID UniProtKB:
ID gene:
  • Human(5153) Summary: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
  • Mouse(18574) phosphodiesterase 1B, Ca2+-calmodulin dependent
  • Rat(29691) phosphodiesterase 1B, calmodulin-dependent
  • Domestic Rabbit(100341084) phosphodiesterase 1B, calmodulin-dependent
  • naked mole-rat(101718122) phosphodiesterase 1B, calmodulin-dependent
  • domestic guinea pig(100527959) phosphodiesterase 1B, Ca2+-calmodulin dependent
  • cow(281970) phosphodiesterase 1B, calmodulin-dependent
  • sheep(101118773) phosphodiesterase 1B, calmodulin-dependent
  • dog(100856025) phosphodiesterase 1B, calmodulin-dependent
  • Horse(100064711) phosphodiesterase 1B, calmodulin-dependent
  • domestic cat(101094608) phosphodiesterase 1B, calmodulin-dependent

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-PDE1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Monoclonal Anti-PDE1B, (C-terminal) antibody produced in mouse, clone 4F9, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
8-Methoxymethyl-3-isobutyl-1-methylxanthine, ≥98%,
Specie
human
Vinpocetine, ≥98%, solid,
Specie
human
Theophylline, anhydrous, ≥99%, powder,
Specie
mouse, human, rat
Rolipram, solid, ≥98% (HPLC),
Specie
human, mouse, rat
Dipyridamole, United States Pharmacopeia (USP) Reference Standard,
Specie
human

Proteins

N° Catalogo
Descrizione
Specie
PDE1B Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Specie
human
PDE1B active rat, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE),
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human PDE1B,
Specie
human
MISSION® esiRNA, targeting mouse Pde1b,
Specie
mouse