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Merck

HDAC3

histone deacetylase 3

Sinonimi:
HD3, RPD3, RPD3-2
Specie:
Human HDAC3 (8841), Mouse Hdac3 (15183), Rat Hdac3 (84578), sheep HDAC3 (101107092), domestic guinea pig Hdac3 (100718985), naked mole-rat Hdac3 (101708680), Zebrafish hdac3 (393965), cow HDAC3 (404125), domestic cat HDAC3 (101100941), dog HDAC3 (478040) ...Più
ID UniProtKB:
O15379, D3DQE1, O43268, Q9UEI5, Q9UEV0
ID gene:
  • Human(8841) Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]
  • Mouse(15183) histone deacetylase 3
  • Rat(84578) histone deacetylase 3
  • sheep(101107092) histone deacetylase 3
  • domestic guinea pig(100718985) histone deacetylase 3
  • naked mole-rat(101708680) histone deacetylase 3
  • Zebrafish(393965) histone deacetylase 3
  • cow(404125) histone deacetylase 3
  • domestic cat(101100941) histone deacetylase 3
  • dog(478040) histone deacetylase 3
  • chicken(395506) histone deacetylase 3
  • fruit fly(44446) Histone deacetylase 3

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
SAB4301541
Anti-phospho-HDAC3 (pSer424) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
western blot
HPA052052
Anti-HDAC3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
western blot
06-890
Anti-HDAC3 Antibody, Upstate®, from rabbit,
Reattività con
human, mouse, rat
Applicazione
western blot
WH0008841M2
Monoclonal Anti-HDAC3 antibody produced in mouse, clone 3E11, purified immunoglobulin, buffered aqueous solution,
Reattività con
human, mouse, rat
Applicazione
ELISA
western blot
SAB4503481
Anti-HDAC3 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunofluorescence
immunohistochemistry
western blot

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
SML0061
SAHA, ≥98% (HPLC),
Specie
human
SML1175
Romidepsin, ≥98% (HPLC),
Specie
human
C0621
CI−994, ≥98% (HPLC), powder,
Specie
human

Proteins

N° Catalogo
Descrizione
Specie
SRP2072
HDAC3 human, recombinant, expressed in insect cells, ≥70% (SDS-PAGE),
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
EHU035581
MISSION® esiRNA, targeting human HDAC3,
Specie
human
EMU090241
MISSION® esiRNA, targeting mouse Hdac3,
Specie
mouse