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A3648

Sigma-Aldrich

(3-Aminopropyl)triethoxysilane

≥98%

Synonym(s):

APTS, 3-Triethoxysilylpropylamine, APTES

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About This Item

Linear Formula:
H2N(CH2)3Si(OC2H5)3
CAS Number:
919-30-2
Molecular Weight:
221.37
Beilstein:
1754988
EC Number:
213-048-4
MDL number:
MFCD00008207
UNSPSC Code:
12171500
PubChem Substance ID:
24890794
NACRES:
NA.47

Quality Level

200

Assay

≥98%

form

liquid

pH

11 (20 °C, 20 g/L)

bp

217 °C/760 mmHg (lit.)

mp

220-222 °C

density

0.946 g/mL at 25 °C (lit.)

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

CCO[Si](CCCN)(OCC)OCC

InChI

1S/C9H23NO3Si/c1-4-11-14(12-5-2,13-6-3)9-7-8-10/h4-10H2,1-3H3

InChI key

WYTZZXDRDKSJID-UHFFFAOYSA-N

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Application

  • (3-Aminopropyl)triethoxysilane has been used for the preparation of cadherin surfaces on glass slides.
  • It has been used for the preparation of RGD (Arg-Gly-Asp)-treated silicone membranes.
  • It has been used for the preparation of the avidin–biotin coverslips.

Biochem/physiol Actions

(3-Aminopropyl)triethoxysilane forms aminopropyl derivative of glass, an adsorbent for affinity chromatography. It is used to prepare positively charged slides suitable for use with various immunohistochemical and in situ hybridization procedures.

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H302,H314,H317

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

199.4 °F - closed cup

Flash Point(C)

93 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
WXBD6316V
WXBD5034V
WXBC7792V
WXBD4592V
WXBD3620V

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Apoptosis and survival of osteoblast-like cells are regulated by surface attachment.
Grigoriou V, et al.
The Journal of Biological Chemistry, 280, 1733-1739 (2005)
Real-time observation of a single DNA digestion by lambda exonuclease under a fluorescence microscope field.
Matsuura S, et al.
Nucleic Acids Research, 29, E79-E79 (2001)
Dan Zheng et al.
Talanta, 99, 22-28 (2012-09-13)
A mediatorless glucose biosensor was developed by the immobilization of glucose oxidase (GOx) to graphene-functionalized glassy carbon electrode (GCE). The surface of GCE was functionalized with graphene by incubating it with graphene dispersed in 3-aminopropyltriethoxysilane (APTES), which acted both as
Vladimir Gubala et al.
Analytica chimica acta, 760, 75-82 (2012-12-26)
Herein a simple analytical method is presented for the characterization of biomolecule adsorption on cyclo olefin polymer (COP, trade name: Zeonor(®)) substrates which are widely used in microfluidic lab-on-a-chip devices. These Zeonor(®) substrates do not possess native functional groups for
Peng Yuan et al.
Nanotechnology, 23(37), 375705-375705 (2012-08-28)
The surfaces of naturally occurring halloysite nanotubes were functionalized with γ-aminopropyltriethoxysilane (APTES), which was found to have a substantial effect on the loading and subsequent release of a model dye molecule. APTES was mostly anchored at the internal lumen surface
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