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Key Documents

L091000

Sigma-Aldrich

N,N-Dimethylformamide

Synonym(s):

DMF, NSC 5356

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About This Item

Linear Formula:
HCON(CH3)2
CAS Number:
Molecular Weight:
73.09
Beilstein:
605365
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.51

vapor density

2.5 (vs air)

Quality Level

vapor pressure

2.7 mmHg ( 20 °C)

type

for DNA synthesis

product line

Proligo Reagents

form

liquid

autoignition temp.

833 °F

expl. lim.

15.2 %

storage condition

dry at room temperature

impurities

≤200 ppm water content (Karl Fischer)
≤9 ppm Amine content

color

clear

refractive index

n20/D 1.430 (lit.)

pH

6.7

bp

153 °C (lit.)

mp

−61 °C (lit.)

density

0.944 g/mL (lit.)

SMILES string

[H]C(=O)N(C)C

InChI

1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3

InChI key

ZMXDDKWLCZADIW-UHFFFAOYSA-N

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General description

N,N-Dimethylformamide (DMF) is an amide that works as a multipurpose reagent that is an effective polar solvent for various compounds and a ligand for metallic compounds. It also acts as a key intermediate as an electrophilic or nucleophilic agent for mediating reactions as it delivers its own H, C, N, and O atoms in compound synthesis.

Application

DMF is a widely used polar solvent in which organic, organometallic, and bioorganic transformations are carried out. It is also a solvent for many hydrophobic organic compounds and acts as a source of building blocks in various organic synthesis reactions.
Solvent for many hydrophobic organic compounds.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 1B

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

135.5 °F - closed cup

Flash Point(C)

57.5 °C - closed cup


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH SVHC Candidate List

CAS No.

EU REACH Annex XVII (Restriction List)

CAS No.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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