• How to Prep DNA and RNA using GenElute™-E Single Spin Purification Kits

  Demo video showing how to purify DNA and RNA GenElute™-E single spin nucleic acid purification kits.

• /IE/en/technical-documents/technical-article/genomics/sequencing/multi-seq-sample-multiplexing-single-cell-analysis-sequencing

• Autophagy in Cancer Promotes Therapeutic Resistance

  This article provides insight into the mechanisms by which autophagy can protect cancer cells from the effects of anticancer treatments.

• Discovery at Single-Cell Resolution

  CRISPR lentiviral screening libraries are powerful research tools. Continuing a decade long commitment to library screening manufacturing, we have partnered with 10x Genomics to bring 10x Feature Barcode-compatible pooled screening products to you.

• CRISPR Essentials: MISSION^® CRISPR gRNAs, Cas9 and Related Products

  Compare and contrast the features of a wide variety of guide RNA (gRNA) and Cas9 products for in vitro and in vivo CRISPR experiments.

• The Researcher’s Guide to Designing CRISPR and RNAi Screening Experiments

  This screening guide covers how to choose a cell line, a screening library, and experimental conditions as well as tips for designing and performing your experiment.

Antibodies

• Antibody Enhanced-Validation Strategies

  Antibody enhanced validation provides additional data to help ensure antibody specificity and performance and to address antibody reproducibility crisis.

• Prestige Antibodies^® in Breast Cancer Research

  Browse Human Protein Atlas; Prestige Antibodies^®; Polyclonals and Monoclonals; Clinical Markers; Antibodies used in breast cancer research.

• Immunohistochemistry Applications in Gastrointestinal Cancer

  Colorectal cancer is the third most common cancer in both men and women. An estimated 136,000 cases of colorectal cancer are expected to occur in 2016.

• Immunohistochemistry Applications in Breast Cancer

  Immunohistochemistry (IHC) is used to characterize intracellular proteins or various cell surfaces in all tissues. Individual markers or more often panels of various marker proteins can be used to characterize various tumor subtypes, confirm tissue of origin, distinguish metastatic from primary tumor and provide additional information which may be important for prognosis, predicting response to therapy or evaluating residual tumour post-treatment.

• Tissue Markers for Cancer Diagnostics

  Immunohistochemistry (IHC) represents an indispensable tool in cancer diagnostics.

Immunoassay Kits and Platforms

• Overview of Luminex^® Multiplex Assay Technology

  Discover the benefits of MILLIPLEX^® multiplex assays, based on Luminex^® xMAP^® multiplex assay technology, that provide consistent, high-quality results. See how these multiplex biomarker Luminex^® assays are being used to advance research for immunology, cancer, veterinary medicine, metabolism/endocrinology, and more.

• Multiplexing Cancer & Metastasis Signaling Pathways

  Learn how multiplexing with MILLIPLEX^® multiplex assays can help simplify cancer research by measuring multiple circulating biomarkers at once. Find multiplex panels to analyze JAK-STAT, mTOR, MAPK, SAPK, TGFβ signaling pathways, and more.

• Autoantibody Multiplex Analysis

  Multiplex analysis of autoantibodies, such as MILLIPLEX^® multiplex assays, helps advance research by detecting multiple autoantibodies like cytokine autoantibodies, autoimmune autoantibodies, and cancer autoantibodies at once to give researchers a full picture of analyte concentrations.

• Multiplex Cancer Assays for Cancer Biomarker Detection

  Detection of cancer biomarkers through multiplex cancer assays can accelerate studies of normal homeostasis and tumorigenic processes. See how MILLIPLEX^® multiplex cancer assays are advancing various cancer research areas including lung cancer, breast cancer, and immuno-oncology research.

• Multiplex Cancer Assays for Cancer Biomarker Detection

  Detection of cancer biomarkers through multiplex cancer assays can accelerate studies of normal homeostasis and tumorigenic processes. See how MILLIPLEX^® multiplex cancer assays are advancing various cancer research areas including lung cancer, breast cancer, and immuno-oncology research.

• Multiplexing Cancer & Metastasis Signaling Pathways

  Learn how multiplexing with MILLIPLEX^® multiplex assays can help simplify cancer research by measuring multiple circulating biomarkers at once. Find multiplex panels to analyze JAK-STAT, mTOR, MAPK, SAPK, TGFβ signaling pathways, and more.

Protein Electrophoresis & Western Blotting

• Western Blotting Sample Preparation

  Rules and good practice in sample preparation for Western blot sample preparation from cell culture and tissue samples.

• Auto2D^® Automated 2-D Gel Electrophoresis Device

  The Auto2D^® Automated 2-D Electrophoresis Device fully automates difficult 2D electrophoresis methods in a quick, easy, and reproducible way. Locate difficult-to-find proteins using the Auto2D^® system in less than two hours with high reproducibility.

• Fatty Acid Synthesis and Metabolism in Cancer Cells

  Information on fatty acid synthesis and metabolism in cancer cells. Learn how proliferatively active cells require fatty acids for functions such as membrane generation, protein modification, and bioenergetic requirements. These fatty acids are derived either from dietary sources or are synthesized by the cell.

• Angiostatin and Endostatin: Key Players in a Dual Threat Approach to Cancer Treatment

  Anticancer drugs development - natural and synthetic angiogenesis inhibitors.

• Long-Term Live Cell Tracking of Cancer and Stem Cells Using a Biocompatible Fluorescent Nanoparticle Based Upon Aggregation Induced Emission (AIE Dot) Nanotechnology

  Biocompatible organic fluorescent nanoparticles (AIE Dots) that can be used to label cells and vasculature for long-term live cell tracking and tracing experiments.

• How to Optimize the Duolink^® Proximity Ligation Assay

  To successfully execute a Duolink^® PLA experiment, there are some necessary considerations to properly prepare for, setup, and execute the assay protocol.