Chromatography Systems for Bioprocessing

Single-use and multi-use chromatography systems are critical factors for the successful separation of your valuable molecules. From pilot to process-scale, our systems are designed to provide robust, consistent performance with the processing flexibility you need. We also offer an unmatched portfolio of chromatography resins and membranes, backed by unparalleled applications and validation support. With this complete product offering, we continue to support you in your efforts to increase productivity and process efficiency. Our experts can help you find the right product for your chromatography process. 

Mobius^® Multi Column Capture System

The Mobius^® Multi Column Capture system is a fully automated, single-use solution to operate continuous closed capture chromatography. It manages process parameters in real time with reference to changing column load, surge feed tank load, and monitoring resin performance. Coupled with an in-line dilution capability and intuitive software, the 3 columns system allows complete control of the capture step of your fed-batch or perfusion bioprocess. The Mobius^® Multi Column Capture system is suitable for bioreactor volumes ranging from 50 L to 2000 L.  Learn more on multi column chromatography.

Mobius^® Chrom 20 system

The Mobius^® Chrom 20 system is a flexible, fully automated, single-use chromatography system that enables consistent and reliable separation and purification of mAbs, vaccines, plasma, and therapeutic proteins at clinical and commercial scales. The innovative single-use flowpath reduces contamination risk while the flexible design features a standard hardware platform and options, empowering you to meet your unique process requirements. The Mobius^® Chrom 20 system delivers optimal operational flexibility for a 2,000 L bioreactor scale, with flow rates from 0.4 L/min (isocratic mode) up to 20 L/min. In gradient mode the system covers flow rates from 4 L/min to 20 L/min, for a 5:1 turn down ratio, with unrivalled isocratic and linear gradient accuracy.

Mobius^® FlexReady Solution for chromatography

The Mobius^® FlexReady Solution with Smart Flexware^® Assemblies is a flexible system, allowing you to have a single, scalable system for chromatography. The fully automated system is designed to achieve separation and purification of mAbs, vaccines, plasma, and therapeutic proteins. The Mobius^® FlexReady Solution with Smart Flexware^® Assemblies delivers optimal operational flexibility in a very simple and fast way.

CoPrime^® biochromatography systems

CoPrime^® biochromatography systems are designed to achieve optimum separation and purification of monoclonal antibodies, vaccines, plasma, and therapeutic proteins. The systems support rapid scale-up and are ideally suited for pilot and process scale. They are based on 50 years of process knowledge and engineering expertise, providing a configurable, intuitive process-scale purification solution. CoPrime^® B and C sizes have an extended flow rate span and optimized performance for greater gradient accuracy and purification reproduction. The CoPrime^® size C covers higher scales and allows scale-up directly from CoPrime™ B.

Data Sheet: Mobius^® Multi Column Capture System
Performance Guide: Mobius^® Multi Column Capture System
Spare Parts List: Mobius^® Multi Column Capture System
Application Note: Multi-Column Capture
Data Sheet: Mobius^® Chrom 20 System
Spare Parts List: Mobius^® Chrom 20 System
Data Sheet: CoPrime^® Biochromatography Process-Scale System

Spec. Sheet: Mobius^® FlexReady Solution with Smart Flexware^® Assemblies for TFF
Data Sheet: Mobius^® FlexReady Solution with Smart Flexware^® Assemblies for Chromatography and TFF
Spare Parts List: Mobius^® FlexReady Solution
Poster: Horizon 2020 - Fully Connected Single-use Downstream Platform for mAb Production